In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …

Multivalent nanoconstructs, extensively used for enhancing the recognition of biomolecular
targets, have been recently exploited for enzyme inhibition showing interesting properties …

Rapid change and zoonotic transmission to humans have enhanced the virulence of the
influenza A virus (IAV). Neutralizing antibodies fail to provide lasting protection from …

The ability of antibodies to bind a wide variety of analytes with high specificity and high
affinity makes them ideal candidates for therapeutic and diagnostic applications. However …

Polyvalent interactions, where multiple ligands and receptors interact simultaneously, are
ubiquitous in nature. Synthetic polyvalent molecules, therefore, have the ability to affect …

Chemical linkers are frequently used in enzyme immobilization to improve enzyme flexibility
and activity, whereas peptide linkers, although ubiquitous in protein engineering, are much …

The design of smart nonviral vectors for gene delivery is of prime importance for the
successful implementation of gene therapies. In particular, degradable analogues of …

The construction of a multivalent ligand is an effective way to increase affinity and selectivity
toward biomolecular targets with multiple-ligand binding sites. Adopting this strategy, we …

Supramolecular protein assemblies have garnered considerable interest due to their
potential in diverse fields with unrivaled attainable functionalities and structural accuracy …

A molecular bottlebrush functionalized magnetic adsorbent (magGO@ bottlebrush) was
fabricated in this work. Poly (hydroxyethyl methacrylate)(PHEMA) was first grafted from …