Summary Leukotriene B4 (LTB4) was recognized as an arachidonate‐derived chemotactic
factor for inflammatory cells and an important drug target even before the molecular …

Neutrophil swarming is a complex coordinated process in which neutrophils sensing
pathogen or damage signals are rapidly recruited to sites of infections or injuries. This …

Neutrophils are the primary cell type involved in lung ischemia-reperfusion injury (IRI), which
remains a frequent and morbid complication after organ transplantation. Endogenous lipid …

Abstract Leukotriene B4 (LTB4) is a potent lipid chemoattractant driving inflammatory
responses during host defense, allergy, autoimmune and metabolic diseases. Gradients of …

Neutrophil swarming is an essential process of the neutrophil response to many
pathological conditions. Resultant neutrophil accumulations are hallmarks of acute tissue …

Invasive fungal infections are life-threatening, and neutrophils are vital cells of the innate
immune system that defend against them. The role of LTA4H-LTB4-BLT1 axis in regulation …

Specialized proresolving mediators (SPMs) promote local macrophage efferocytosis but
excess leukocytes early in inflammation require additional leukocyte clearance mechanism …

Neutrophils play a primary role in protecting our body from pathogens. When confronted with
invading bacteria, neutrophils begin to produce leukotriene B4, a potent chemoattractant …

The phenomenon of swarming has long been observed in nature as a strategic event that
serves as a good offense toward prey and predators. Imaging studies have uncovered that …

The leucine-rich repeat-containing G-protein–coupled receptor 6 (LGR6) was recently
identified as the cognate receptor for the proresolving mediator maresin 1 (MaR1). To …