Urban informal settlements as hotspots of antimicrobial resistance and the need to curb environmental transmission

ML Nadimpalli, SJ Marks, MC Montealegre… - Nature …, 2020 - nature.com
Antimicrobial resistance (AMR) is a growing public health challenge that is expected to
disproportionately burden lower-and middle-income countries (LMICs) in the coming …

Worldwide Prevalence of mcr-mediated Colistin-Resistance Escherichia coli in Isolates of Clinical Samples, Healthy Humans, and Livestock—A Systematic Review …

C Bastidas-Caldes, JH de Waard, MS Salgado… - Pathogens, 2022 - mdpi.com
Background: Antimicrobial resistance is a serious public-health problem throughout the
world. Escherichia coli, the most common Gram-negative microorganism, has developed …

[HTML][HTML] Global prevalence and molecular epidemiology of mcr-mediated colistin resistance in Escherichia coli clinical isolates: A systematic review

M Dadashi, F Sameni, N Bostanshirin… - Journal of global …, 2022 - Elsevier
Objectives The continuing rise in infections caused by multidrug-resistant (MDR) bacteria is
one of the most serious public-health issues in society today. Colistin is a last-resort …

Carbapenem and colistin resistance in Enterobacteriaceae in Southeast Asia: review and map** of emerging and overlap** challenges

MD Malchione, LM Torres, DM Hartley, M Koch… - International journal of …, 2019 - Elsevier
Carbapenem-resistant Enterobacteriaceae infections have spread globally, leaving
polymyxins, including colistin, as 'last-resort treatments'. Emerging colistin resistance raises …

High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be …

AMS Shein, DL Wannigama, PG Higgins, C Hurst… - Scientific Reports, 2022 - nature.com
The global prevalence of colistin-resistant Klebsiella pneumoniae (ColRkp) facilitated by
chromosomal and plasmid-mediated Ara4N or PEtN-remodeled LPS alterations has steadily …

Klebsiella oxytoca and Emerging Nosocomial Infections

N Neog, U Phukan, M Puzari, M Sharma, P Chetia - Current Microbiology, 2021 - Springer
Klebsiella oxytoca is rising as a significant opportunistic pathogen causing nosocomial
infections in neonates as well as adults. This pathogen's prevalence varies from 2 to 24 …

Improved lyophilization conditions for long-term storage of bacteriophages

P Manohar, N Ramesh - Scientific reports, 2019 - nature.com
Phage therapy is one of the promising alternatives to combat the increasing problem of
antibiotic resistance. Lyophilization is used for the preparation of pharmaceutical products to …

The therapeutic potential of bacteriophages targeting gram-negative bacteria using Galleria mellonella infection model

P Manohar, R Nachimuthu, BS Lopes - BMC microbiology, 2018 - Springer
Background Phage therapy is the therapeutic use of bacteriophages to treat highly drug
resistant bacterial infections. The current surge in bacteriophage therapy is motivated mainly …

The applications of animal models in phage therapy: an update

F Mehmood Khan, P Manohar… - Human Vaccines & …, 2023 - Taylor & Francis
The rapid increase in antibiotic resistance presents a dire situation necessitating the need
for alternative therapeutic agents. Among the current alternative therapies, phage therapy …

Colistin Resistance Among Multiple Sequence Types of Klebsiella pneumoniae Is Associated With Diverse Resistance Mechanisms: A Report From India

M Azam, R Gaind, G Yadav, A Sharma… - Frontiers in …, 2021 - frontiersin.org
Background: The resistance to colistin and carbapenems in Klebsiella pneumoniae
infections have been associated with increased morbidity and mortality worldwide. A …