Epigenetic modifications in stress response genes associated with childhood trauma

S Jiang, L Postovit, A Cattaneo, EB Binder… - Frontiers in …, 2019 - frontiersin.org
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …

Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential

CD Walker, KG Bath, M Joels, A Korosi, M Larauche… - Stress, 2017 - Taylor & Francis
The immediate and long-term effects of exposure to early life stress (ELS) have been
documented in humans and animal models. Even relatively brief periods of stress during the …

Animal models of PTSD: a challenge to be met

G Richter-Levin, O Stork, MV Schmidt - Molecular psychiatry, 2019 - nature.com
Recent years have seen increased interest in psychopathologies related to trauma
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …

Parenting begets parenting: A neurobiological perspective on early adversity and the transmission of parenting styles across generations

AM Lomanowska, M Boivin, C Hertzman, AS Fleming - Neuroscience, 2017 - Elsevier
The develo** brains of young children are highly sensitive to input from their social
environment. Nurturing social experience during this time promotes the acquisition of social …

Cortisol and depression: three questions for psychiatry

J Herbert - Psychological medicine, 2013 - cambridge.org
BackgroundCortisol plays a multifaceted role in major depression disorder (MDD). Diurnal
rhythms are disturbed, there is increased resistance to the feedback action of …

The psychological impact of COVID-19 pandemic on people with multiple sclerosis

F Motolese, M Rossi, G Albergo, D Stelitano… - Frontiers in …, 2020 - frontiersin.org
Objective: The coronavirus disease 2019 (COVID-19) has radically changed the world in a
few weeks. Italy has been one of the first and most affected countries with more than 30,000 …

Prenatal excess glucocorticoid exposure and adult affective disorders: a role for serotonergic and catecholamine pathways

CS Wyrwoll, MC Holmes - Neuroendocrinology, 2012 - karger.com
Fetal glucocorticoid exposure is a key mechanism proposed to underlie prenatal
'programming'of adult affective behaviours such as depression and anxiety. Indeed, the …