In principle, proton therapy offers a substantial clinical advantage over conventional photon
therapy. This is because of the unique depth-dose characteristics of protons, which can be …

The original rationale for proton therapy was its highly conformal depth‐dose distributions
compared to photons, which allow greater sparing of normal tissues and escalation of tumor …

Primary bone tumours are rare, accounting for< 0.2% of malignant neoplasms registered in
the EUROCARE (European Cancer Registry based study on survival and care of cancer …

Chordomas are very rare bone malignant tumours that have had a shortage of effective
treatments for a long time. New treatments are now available for both the local and the …

Platinum nanoparticles (Pt NPs) have a well-established role as a classic heterogeneous
catalyst. Also, Pt has traditionally been employed as a component of organometallic drug …

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until
recently, there was no consensus among experts regarding appropriate clinical …

Radiation therapy plays an integral role in the management of head and neck cancers
(HNCs). While most HNC patients have historically been treated with photon-based …

This document is an update of the British Sarcoma Group guidelines published in 2010. The
aim is to provide a reference standard for the clinical care of patients in the UK with bone …

Among various types of ion species, carbon ions are considered to have the most balanced,
optimal properties in terms of possessing physically and biologically effective dose …

Compared to conventional photon-based external beam radiation (PhXRT), carbon ion
radiotherapy (CIRT) has superior dose distribution, higher linear energy transfer (LET), and …