The healing of an adult skin wound is a complex process requiring the collaborative efforts
of many different tissues and cell lineages. The behavior of each of the contributing cell …

Werner, Sabine, and Richard Grose. Regulation of Wound Healing by Growth Factors and
Cytokines. Physiol Rev 83: 835–870, 2003; 10.1152/physrev. 00032.2002.—Cutaneous …

Fibroblast growth factors (FGFs) and their receptors (FGFRs) regulate numerous cellular
processes. Deregulation of FGFR signalling is observed in a subset of many cancers …

▪ Abstract All materials intended for application in humans as biomaterials, medical devices,
or prostheses undergo tissue responses when implanted into living tissue. This review first …

Impaired wound healing in the elderly presents a major clinical and economic problem. With
the aging population growing in both number and percentage, the importance of …

Injury triggers an organized and complex cascade of cellular and biochemical events that
result in a healed wound. For didactic purposes, the wound healing response can be …

Mammalian cells export most proteins by the endoplasmic reticulum/Golgi-dependent
pathway. However, some proteins are secreted via unconventional, poorly understood …

Reciprocal interactions between epithelium and mesenchyme mediate crucial aspects of
embryonic development and direct the coordinated organogenesis, correct spatial …

Publisher Summary The family of fibroblast growth factors (FGF) is the largest family of
growth factors involved in soft–tissue growth and regeneration. The FGF family includes …

Tissue injury initiates a complex repair process, which in some organisms can lead to the
complete regeneration of a tissue. In mammals, however, the repair of most organs is …