Methods for transfer of exogenous DNA into cells are essential for genetics and molecular
biology, and the lack of effective methods hampers research on many different species of …

Modern genetics research has resulted in significant advances in cell in vitro microinjection
systems. Such systems provide biological and medical practitioners with high volume cell …

Cell microinjection is a technique of precise delivery of substances into cells and is widely
used for studying cell transfection, signaling pathways, and organelle functions …

Single-cell electroporation (SCEP) is a relatively new technique that has emerged in the last
decade or so for single-cell studies. When a large enough electric field is applied to a single …

Compared to robotic injection of suspended cells (eg, embryos and oocytes), fewer attempts
were made to automate the injection of adherent cells (eg, cancer cells and cardiomyocytes) …

Single cell surgery such as manipulation or removal of subcellular components or/and
organelles from single cells is increasingly used for the study of diseases and their causes in …

In this paper, we introduce an indirect pushing based technique for automated
micromanipulation of biological cells. In indirect pushing, an optically trapped glass bead …

Several recent micro-and nanotechnologies have provided novel methods for biological
studies of adherent cells because the small features of these new biotools provide unique …

This paper presents the design and development of a new microinjection system with force
sensing for automated multi-cell injection in genome editing of zebrafish using the …

As an effective method to deliver external materials into biological cells, microinjection has
been widely applied in the biomedical field. However, the knowledge of cell mechanical …