Autoimmune hepatitis (AIH) is an inflammatory liver disease, affecting mainly females,
characterized by elevated transaminase and immunoglobulin G (IgG) levels, interface …

The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …

Testing for liver-related autoantibodies should be included in the workup of patients with
hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not …

Autoimmune hepatitis (AIH) is an immune-mediated liver disorder characterised by female
preponderance, elevated transaminase and immunoglobulin G levels, seropositivity for …

Autoimmune hepatitis is an uncommon idiopathic syndrome of immune-mediated
destruction of hepatocytes, typically associated with autoantibodies. The disease etiology is …

Interface hepatitis, histological hallmark of autoimmune hepatitis (AIH), is a dense portal
mononuclear cell infiltrate invading the parenchyma, consisting of CD4 and CD8 T …

Until recently, little was known about the importance of CD8+ T effectors in promoting and
preventing autoimmune disease development. CD8+ T cells can oppose or promote …

The mechanisms underlying the pathogenesis of autoimmune hepatitis are not fully
understood, though there is growing evidence that genetic predisposition, molecular mimicry …

The liver is an important immunological organ that controls systemic tolerance. The liver
harbors professional and unconventional antigen-presenting cells that are crucial for …

Background and Aims The diverse inflammatory response found in the liver of patients with
autoimmune hepatitis (AIH) is well established, but identification of potentially pathogenic …