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Large expansion of plasma commensal viruses is associated with SIV pathogenesis in Macaca leonina
Y Li, TZ Song, L Cao, HD Zhang, Y Ma, RR Tian… - Science …, 2024 - science.org
Human immunodeficiency virus-1 (HIV-1) infection disrupts the homeostatic equilibrium
between the host and commensal microbes. However, the dynamic changes of plasma …
between the host and commensal microbes. However, the dynamic changes of plasma …
Genomic Evidence for the Nonpathogenic State in HIV-1–Infected Northern Pig-Tailed Macaques
W Pang, Y Shao, XL Zhuang, Y Lu… - Molecular Biology …, 2023 - academic.oup.com
HIV-1 is a highly host-specific retrovirus that infects humans but not most nonhuman
primates. Thus, the lack of a suitable primate model that can be directly infected with HIV-1 …
primates. Thus, the lack of a suitable primate model that can be directly infected with HIV-1 …
Superior intestinal integrity and limited microbial translocation are associated with lower immune activation in SIVmac239-infected northern pig-tailed macaques …
MX Zhang, TZ Song, HY Zheng, XH Wang… - Zoological …, 2019 - pmc.ncbi.nlm.nih.gov
Microbial translocation is a cause of systemic immune activation in HIV/SIV infection. In the
present study, we found a lower CD8+ T cell activation level in Macaca leonina (northern pig …
present study, we found a lower CD8+ T cell activation level in Macaca leonina (northern pig …
Host Restriction Factors APOBEC3G/3F and Other Interferon-Related Gene Expressions Affect Early HIV-1 Infection in Northern Pig-Tailed Macaque (Macaca leonina …
W Pang, JH Song, Y Lu, XL Zhang, HY Zheng… - Frontiers in …, 2018 - frontiersin.org
The northern pig-tailed macaques (NPMs) lack TRIM5α, an antiviral restriction factor, and
instead have TRIM5-CypA. In our previous study, we demonstrated that HIV-1NL4− 3 …
instead have TRIM5-CypA. In our previous study, we demonstrated that HIV-1NL4− 3 …
[HTML][HTML] Transcription factor ZNF683 inhibits SIV/HIV replication through regulating IFNγ secretion of CD8+ T cells
Y Lu, MX Zhang, W Pang, TZ Song, HY Zheng, RR Tian… - Viruses, 2022 - mdpi.com
Pulmonary microbial invasion frequently occurs during AIDS progression in HIV patients.
Inflammatory cytokines and other immunoregulatory factors play important roles in this …
Inflammatory cytokines and other immunoregulatory factors play important roles in this …
Northern pig-tailed macaques (Macaca leonina) infected with SARS-CoV-2 show rapid viral clearance and persistent immune response
TZ Song, HY Zheng, JB Han, XL Feng… - Zoological …, 2021 - pmc.ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has become an unprecedented global health …
syndrome coronavirus (SARS-CoV-2), has become an unprecedented global health …
An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May …
XL Zhang, MT Luo, JH Song, W Pang… - Journal of …, 2020 - journals.asm.org
ABSTRACT APOBEC3 family members, particularly APOBEC3F and APOBEC3G, inhibit the
replication and spread of various retroviruses by inducing hypermutation in newly …
replication and spread of various retroviruses by inducing hypermutation in newly …
Parasites may exit immunocompromised northern pig-tailed macaques (Macaca leonina) infected with SIVmac239
TZ Song, MX Zhang, YJ **a, Y **ao… - Zoological …, 2018 - pmc.ncbi.nlm.nih.gov
Parasites can increase infection rates and pathogenicity in immunocompromised human
immunodeficiency virus (HIV) patients. However, in vitro studies and epidemiological …
immunodeficiency virus (HIV) patients. However, in vitro studies and epidemiological …
Glucose Metabolism Disorder Induces Spermatogenic Dysfunction in Northern Pig-Tailed Macaques (Macaca leonina) With Long-Term SIVmac239 Infection
TZ Song, MX Zhang, HD Zhang, XH Wang… - Frontiers in …, 2021 - frontiersin.org
Although spermatogenic dysfunction is widely found in patients with human
immunodeficiency virus (HIV), the underlying reasons remain unclear. Thus far, potential …
immunodeficiency virus (HIV), the underlying reasons remain unclear. Thus far, potential …
SARS-CoV-2感染北**顶猴(Macaca leonina)呈现病毒快速清除及持续的免疫反应
宋天章， 郑宏毅， **建保， 冯小丽， 刘丰亮， 杨翔， 靳林… - 动物学研究, 2021 - zoores.ac.cn
SARS-CoV-2 感染引起的新型冠状病毒肺炎疫情已成为21 世纪全球最重要的公共卫生突发事件
. 目前, SARS-CoV-2 感染非人灵长类动物模型被认为是进行新型冠状病毒肺炎病理损伤特征及 …
. 目前, SARS-CoV-2 感染非人灵长类动物模型被认为是进行新型冠状病毒肺炎病理损伤特征及 …