The ability of chemical modifications of single nucleotides to alter the electrostatic charge,
hydrophobic surface and base pairing of RNA molecules is exploited for the clinical use of …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …

The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …

Conspectus More than 170 different types of chemical modifications have been identified on
diverse types of RNA, collectively known as the epitranscriptome. Among them, N 6 …

5-methylcytosine (m5C) is one of the most prevalent modifications of RNA, playing important
roles in RNA metabolism, nuclear export, and translation. However, the potential role of RNA …

Transfer RNAs (tRNAs) decode messenger RNA codons to peptides at the ribosome. The
nuclear genome contains many tRNA genes for each amino acid and even each anticodon …

Background The precise temporal and spatial regulation of N5‐methylcytosine (m5C) RNA
modification plays essential roles in RNA metabolism, and is necessary for the maintenance …

The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

Utilization of specific codons varies between organisms. Cancer represents a model for
understanding DNA sequence evolution and could reveal causal factors underlying codon …