The retina is a complex tissue with multiple cell layers that are highly ordered. Its
sophisticated structure makes it especially sensitive to external or internal perturbations that …

Microglia, the immunocompetent cells of the central nervous system (CNS), act as
neuropathology sensors and are neuroprotective under physiological conditions. Microglia …

Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in
the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis is …

Glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …

Diabetic retinopathy is one of the major microvascular complications of diabetes mellitus.
The most common causes of vision loss in diabetic retinopathy are diabetic macular edema …

Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the
retina and a significant cause of irreversible blindness in developed countries. Alzheimer's …

As a common pathology of many ocular disorders such as diabetic retinopathy and
glaucoma, retinal ischemia/reperfusion (IR) triggers inflammation and microglia activation …

Microglia are the resident immune cells of the central nervous system (CNS) and play a key
role in maintaining the normal function of the retina and brain. During early development …

Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein
ligase (PARKIN) genes are associated with familial forms of Parkinson's disease (PD) …

Glaucoma is the second leading cause of blindness worldwide, affecting~ 80 million people
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …