Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Desorption electrospray ionization mass spectrometry: 20 years

NM Morato, RG Cooks - Accounts of chemical research, 2023 - ACS Publications
Conspectus Mass spectrometry (MS) is one of the most widely used technologies in the
chemical sciences. With applications spanning the monitoring of reaction products, the …

Spontaneous reduction-induced degradation of viologen compounds in water microdroplets and its inhibition by host–guest complexation

C Gong, D Li, X Li, D Zhang, D **ng… - Journal of the …, 2022 - ACS Publications
Water serves as an inert environment for the dispersion and application of many kinds of
herbicides. Viologen compounds, a type of widely used but highly toxic herbicide, are stable …

Micrometer-sized water droplets induce spontaneous reduction

JK Lee, D Samanta, HG Nam… - Journal of the American …, 2019 - ACS Publications
Bulk water serves as an inert solvent for many chemical and biological reactions. Here, we
report a striking exception. We observe that in micrometer-sized water droplets …

Organic reactions in microdroplets: Reaction acceleration revealed by mass spectrometry

X Yan, RM Bain, RG Cooks - … Chemie International Edition, 2016 - Wiley Online Library
The striking finding that reaction acceleration occurs in confined‐volume solutions sets up
an apparent conundrum: Microdroplets formed by spray ionization can be used to monitor …

Mass spectrometry imaging under ambient conditions

C Wu, AL Dill, LS Eberlin, RG Cooks… - Mass spectrometry …, 2013 - Wiley Online Library
Mass spectrometry imaging (MSI) has emerged as an important tool in the last decade and it
is beginning to show potential to provide new information in many fields owing to its unique …

Abiotic production of sugar phosphates and uridine ribonucleoside in aqueous microdroplets

I Nam, JK Lee, HG Nam, RN Zare - … of the National Academy of Sciences, 2017 - pnas.org
Phosphorylation is an essential chemical reaction for life. This reaction generates
fundamental cell components, including building blocks for RNA and DNA, phospholipids for …

Accelerated reactions of amines with carbon dioxide driven by superacid at the microdroplet interface

KH Huang, Z Wei, RG Cooks - Chemical Science, 2021 - pubs.rsc.org
Microdroplets display distinctive interfacial chemistry, manifested as accelerated reactions
relative to those observed for the same reagents in bulk. Carbon dioxide undergoes C–N …

Multi‐dimensional mass spectrometry‐based shotgun lipidomics and novel strategies for lipidomic analyses

X Han, K Yang, RW Gross - Mass spectrometry reviews, 2012 - Wiley Online Library
Since our last comprehensive review on multi‐dimensional mass spectrometry‐based
shotgun lipidomics (Mass Spectrom. Rev. 24 (2005), 367), many new developments in the …

Nanospray desorption electrospray ionization: an ambient method for liquid-extraction surface sampling in mass spectrometry

PJ Roach, J Laskin, A Laskin - Analyst, 2010 - pubs.rsc.org
Nanospray desorption electrospray ionization (nano-DESI) mass spectrometry is presented
as an ambient pressure liquid extraction-ionization technique for analysis of organic and …