Multifunctional cationic host defence peptides and their clinical applications

ATY Yeung, SL Gellatly, REW Hancock - Cellular and Molecular Life …, 2011 - Springer
With the rapid rise in the emergence of bacterial strains resistant to multiple classes of
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …

Overview on the recent study of antimicrobial peptides: origins, functions, relative mechanisms and application

Y Li, Q **ang, Q Zhang, Y Huang, Z Su - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs), which are produced by several species including insects,
other animals, micro-organisms and synthesis, are a critical component of the natural …

Microbiome influences on insect host vector competence

B Weiss, S Aksoy - Trends in parasitology, 2011 - cell.com
Insect symbioses lack the complexity and diversity of those associated with higher
eukaryotic hosts. Symbiotic microbiomes are beneficial to their insect hosts in many ways …

Peptide design for antimicrobial and immunomodulatory applications

EF Haney, REW Hancock - Peptide Science, 2013 - Wiley Online Library
The increasing threat of antibiotic resistance in pathogenic bacteria and the dwindling
supply of antibiotics available to combat these infections poses a significant threat to human …

Antimicrobial properties and membrane-active mechanism of a potential α-helical antimicrobial derived from cathelicidin PMAP-36

Y Lv, J Wang, H Gao, Z Wang, N Dong, Q Ma, A Shan - PloS one, 2014 - journals.plos.org
Antimicrobial peptides (AMPs), which present in the non-specific immune system of
organism, are amongst the most promising candidates for the development of novel …

Antimicrobial peptides in farm animals: an updated review on its diversity, function, modes of action and therapeutic prospects

R Kumar, SA Ali, SK Singh, V Bhushan, M Mathur… - Veterinary …, 2020 - mdpi.com
Antimicrobial peptides (AMPs) are the arsenals of the innate host defense system, exhibiting
evolutionarily conserved characteristics that are present in practically all forms of life. Recent …

Antimicrobial peptide action on parasites

M Torrent, D Pulido, L Rivas, D Andreu - Current drug targets, 2012 - ingentaconnect.com
Diseases caused by protozoan parasites can pose a severe thread to human health and are
behind some serious neglected tropical diseases like malaria and leishmaniasis. Though …

Apoptotic markers in protozoan parasites

A Jiménez-Ruiz, JF Alzate, ET MacLeod, CGK Lüder… - Parasites & vectors, 2010 - Springer
The execution of the apoptotic death program in metazoans is characterized by a sequence
of morphological and biochemical changes that include cell shrinkage, presentation of …

Human antimicrobial peptides in ocular surface defense

I Mohammed, DG Said, HS Dua - Progress in retinal and eye research, 2017 - Elsevier
Sight depends on the passage of light through the transparent cornea and being focused on
the fovea. Its exposed position renders it vulnerable to microbial infection. The cornea has …

Designed multifunctional peptides for intracellular targets

D Juretić - Antibiotics, 2022 - mdpi.com
Nature's way for bioactive peptides is to provide them with several related functions and the
ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as …