Functional mitochondria in health and disease
The ability to rapidly adapt cellular bioenergetic capabilities to meet rapidly changing
environmental conditions is mandatory for normal cellular function and for cancer …
environmental conditions is mandatory for normal cellular function and for cancer …
Multi-targeted therapy of cancer by genistein
S Banerjee, Y Li, Z Wang, FH Sarkar - Cancer letters, 2008 - Elsevier
Soy isoflavones have been identified as dietary components having an important role in
reducing the incidence of breast and prostate cancers in Asian countries. Genistein, the …
reducing the incidence of breast and prostate cancers in Asian countries. Genistein, the …
Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer
Elevated lifetime estrogen exposure is a major risk factor for breast cancer. Recent
advances in the understanding of breast carcinogenesis clearly indicate that induction of …
advances in the understanding of breast carcinogenesis clearly indicate that induction of …
Cancers take their Toll—the function and regulation of Toll-like receptors in cancer cells
Cancer could be deemed as an abnormal and uncontrolled tissue repair process. Therefore,
it would not be surprising that factors that function in the tissue repair process, such as …
it would not be surprising that factors that function in the tissue repair process, such as …
Inflammation, cancer and chemoresistance: taking advantage of the toll‐like receptor signaling pathway
The association between chronic inflammation and cancer has long been observed.
Furthermore, NF‐κB activation and the subsequent production of cytokines, chemokines …
Furthermore, NF‐κB activation and the subsequent production of cytokines, chemokines …
Stem-like ovarian cancer cells can serve as tumor vascular progenitors
Neovascularization is required for solid tumor maintenance, progression, and metastasis.
The most described contribution of cancer cells in tumor neovascularization is the secretion …
The most described contribution of cancer cells in tumor neovascularization is the secretion …
Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs
F H. Sarkar, Y Li, Z Wang… - Current pharmaceutical …, 2010 - benthamdirect.com
In recent years, naturally occurring dietary compounds have received greater attention in the
field of cancer prevention and treatment research. Among them, isoflavone genistein and …
field of cancer prevention and treatment research. Among them, isoflavone genistein and …
Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells
Cancer stem cells are responsible for tumor initiation and chemoresistance. In ovarian
cancer, the CD44+/MyD88+ ovarian cancer stem cells are also able to repair the tumor and …
cancer, the CD44+/MyD88+ ovarian cancer stem cells are also able to repair the tumor and …
p53–Pirh2 complex promotes Twist1 degradation and inhibits EMT
Y Yang-Hartwich, R Tedja, CM Roberts… - Molecular Cancer …, 2019 - AACR
Epithelial–mesenchymal transition (EMT) is a critical process involved in cancer metastasis
and chemoresistance. Twist1 is a key EMT-inducing transcription factor, which is …
and chemoresistance. Twist1 is a key EMT-inducing transcription factor, which is …
Adipocyte microenvironment promotes Bclxl expression and confers chemoresistance in ovarian cancer cells
C Cardenas, MK Montagna, M Pitruzzello, E Lima… - Apoptosis, 2017 - Springer
Resistance to mitochondria-initiated apoptosis is a hallmark of chemoresistant cancer stem
cells including CD44+/MyD88+ epithelial ovarian cancer (EOC) stem cells. This is controlled …
cells including CD44+/MyD88+ epithelial ovarian cancer (EOC) stem cells. This is controlled …