Effect of model, observer and their interaction on state and disturbance estimation in artificial pancreas: An in-silico study

I Sala-Mira, M Siket, L Kovács, G Eigner… - IEEE Access, 2021 - ieeexplore.ieee.org
The state and disturbance estimations are an indispensable part of the state-of-the-art model-
based controllers as related to the artificial pancreas, supporting the decision-making and …

A bolus calculator based on continuous-discrete unscented Kalman filtering for type 1 diabetics

D Boiroux, TB Aradóttir, M Hagdrup, NK Poulsen… - IFAC-PapersOnLine, 2015 - Elsevier
In patients with type 1 diabetes, the effects of meals intake on blood glucose level are
usually mitigated by administering a large amount of insulin (bolus) at mealtime or even …

Estimation of insulin sensitivity in diabetic Göttingen Minipigs

BJE Misgeld, PG Tenbrock, K Lunze, JW Dietrich… - Control Engineering …, 2016 - Elsevier
In patients with type 1 diabetes mellitus, insulin sensitivity is a parameter which strongly
affects insulin therapy. Due to its time-dependent variation, this parameter can improve the …

New contributions towards meal and exercise announcement-free artificial pancreas systems

I Sala Mira - 2023 - riunet.upv.es
[ES] Las infusiones exógenas de insulina son vitales para las personas con diabetes tipo 1
para suplir parcialmente la incapacidad del páncreas de secretar insulina. Sin embargo, las …

Long-term prediction for T1DM model during state-feedback control

P Szalay, Z Benyó, L Kovács - 2016 12th IEEE International …, 2016 - ieeexplore.ieee.org
Avoiding low glucose concentration is critically important in type-1 diabetes treatment.
Predicting the future plasma glucose levels could ensure the safety of the patient. However …

State estimation in type 2 diabetes using the continuous-discrete unscented Kalman filter

HG Clausen, J Leth, T Knudsen, H Schiøler - IFAC-PapersOnLine, 2020 - Elsevier
Using a nonlinear model for the glucose-insulin dynamics in type 2 diabetes, formulated in
continuous-time as a stochastic differential equation, we seek to estimate the system states …

Discrete LPV modeling of diabetes mellitus for control purposes

G Eigner, M Siket, A Szakál, I Rudas… - … on Systems, Man, and …, 2018 - ieeexplore.ieee.org
The utilization of modern and advanced control engineering related methods for the control,
estimation and assessment of physiological applications is widespread. It is also well-known …

Reduced-order filtering for insulin sensitivity estimation under external disturbances

BJE Misgeld, PG Tenbrock… - 2017 American Control …, 2017 - ieeexplore.ieee.org
Insulin sensitivity is known to be an endogenous time-varying parameter in glucose
metabolism. A real-time available quantification of insulin sensitivity is advantageous, if used …

Physiological modeling and control at Obuda University

L Kovács, T Ferenci, J Sápi, G Eigner… - 2015 IEEE 10th …, 2015 - ieeexplore.ieee.org
The paper gives a summary of 2014 year results in the topic of physiological modeling and
control achieved by the Physiological Controls Group of the Obuda University. The …

Glycemic monitoring in critical care using nonlinear state estimators

E Aguirre-Zapata, J Cardenas-Cartagena… - IFAC-PapersOnLine, 2017 - Elsevier
As it is already known, patients under physiological stress, ie, during a stay at an intensive
care unit (ICU), often experience stress-induced hyperglycemia and insulin resistance even …