Status and prospects of genome‐wide association studies in plants
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …
tool for the investigation of complex traits. In large part, this was fueled by advances in …
Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …
evolutionary biology. The recent development of cost-effective methods for obtaining high …
Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species
Effective utilization of wild relatives is key to overcoming challenges in genetic improvement
of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …
of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …
A generalized linear mixed model association tool for biobank-scale data
Compared with linear mixed model-based genome-wide association (GWA) methods,
generalized linear mixed model (GLMM)-based methods have better statistical properties …
generalized linear mixed model (GLMM)-based methods have better statistical properties …
GAPIT version 3: boosting power and accuracy for genomic association and prediction
Genome-wide association study (GWAS) and genomic prediction/selection (GP/GS) are the
two essential enterprises in genomic research. Due to the great magnitude and complexity …
two essential enterprises in genomic research. Due to the great magnitude and complexity …
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations
P Qin, H Lu, H Du, H Wang, W Chen, Z Chen, Q He… - Cell, 2021 - cell.com
Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to
crop evolution, domestication, and improvement. Here, we assembled 31 high-quality …
crop evolution, domestication, and improvement. Here, we assembled 31 high-quality …
rMVP: a memory-efficient, visualization-enhanced, and parallel-accelerated tool for genome-wide association study
Along with the development of high-throughput sequencing technologies, both sample size
and SNP number are increasing rapidly in genome-wide association studies (GWAS), and …
and SNP number are increasing rapidly in genome-wide association studies (GWAS), and …
Computationally efficient whole-genome regression for quantitative and binary traits
Genome-wide association analysis of cohorts with thousands of phenotypes is
computationally expensive, particularly when accounting for sample relatedness or …
computationally expensive, particularly when accounting for sample relatedness or …
[HTML][HTML] Pan-genome of wild and cultivated soybeans
Y Liu, H Du, P Li, Y Shen, H Peng, S Liu, GA Zhou… - Cell, 2020 - cell.com
Soybean is one of the most important vegetable oil and protein feed crops. To capture the
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …
Pangenome analysis reveals genomic variations associated with domestication traits in broomcorn millet
Broomcorn millet (Panicum miliaceum L.) is an orphan crop with the potential to improve
cereal production and quality, and ensure food security. Here we present the genetic …
cereal production and quality, and ensure food security. Here we present the genetic …