Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding
Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …
Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation
Bacterial biofilms are communities of bacteria that exist as aggregates that can adhere to
surfaces or be free-standing. This complex, social mode of cellular organization is …
surfaces or be free-standing. This complex, social mode of cellular organization is …
Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
The healthcare industry is in dire need of rapid microbial identification techniques for
treating microbial infections. Microbial infections are a major healthcare issue worldwide, as …
treating microbial infections. Microbial infections are a major healthcare issue worldwide, as …
Chemical composition, antibacterial activity and study of the interaction mechanisms of the main compounds present in the Alpinia galanga rhizomes essential oil
C Zhou, C Li, S Siva, H Cui, L Lin - Industrial Crops and Products, 2021 - Elsevier
In this research, the antibacterial activity and the interaction mechanisms of the major
chemical constituent present in the Alpinia galanga rhizomes essential oil (AGREO) were …
chemical constituent present in the Alpinia galanga rhizomes essential oil (AGREO) were …
Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:XTM
MY Rennie, D Dunham, L Lindvere-Teene, R Raizman… - Diagnostics, 2019 - mdpi.com
The persistent presence of pathogenic bacteria is one of the main obstacles to wound
healing. Detection of wound bacteria relies on sampling methods, which delay confirmation …
healing. Detection of wound bacteria relies on sampling methods, which delay confirmation …
[HTML][HTML] Metabolic heterogeneity in clonal microbial populations
Highlights•Cells of clonal microbial populations can vary in metabolite levels and metabolic
fluxes.•Ecological factors, inherent dynamics and molecular noise cause metabolic …
fluxes.•Ecological factors, inherent dynamics and molecular noise cause metabolic …
Environmental drivers of metabolic heterogeneity in clonal microbial populations
Highlights•Phenotypic heterogeneity in metabolism is driven by nutrient limitation.•Nutrient
limitation underpins metabolic heterogeneity caused by temporal fluctuations in substrate …
limitation underpins metabolic heterogeneity caused by temporal fluctuations in substrate …
Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) has complex and dynamic interactions with the human
host, and subpopulations of Mtb that emerge during infection can influence disease …
host, and subpopulations of Mtb that emerge during infection can influence disease …
[HTML][HTML] Optical methods for bacterial detection and characterization
Rapid identification and enumeration of bacteria are critical, given the surge of antibiotic-
resistance, global exchange of food products, and the use of bacteria for bioremediation …
resistance, global exchange of food products, and the use of bacteria for bioremediation …
[HTML][HTML] Itaconic acid and dimethyl itaconate exert antibacterial activity in carbon-enriched environments through the TCA cycle
LY **e, YB Xu, XQ Ding, S Liang, DL Li, AK Fu… - Biomedicine & …, 2023 - Elsevier
Itaconic acid (IA), a metabolite generated by the tricarboxylic acid (TCA) cycle in eukaryotic
immune cells, and its derivative dimethyl itaconate (DI) exert antibacterial functions in …
immune cells, and its derivative dimethyl itaconate (DI) exert antibacterial functions in …