Super-resolution ultrasound imaging
The majority of exchanges of oxygen and nutrients are performed around vessels smaller
than 100 μm, allowing cells to thrive everywhere in the body. Pathologies such as cancer …
than 100 μm, allowing cells to thrive everywhere in the body. Pathologies such as cancer …
Genetic dissection of neural circuits: a decade of progress
Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
The Allen mouse brain common coordinate framework: a 3D reference atlas
Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …
connections in the mouse brain, collecting large amounts of data across modalities, spatial …
Comprehensive evaluation of the 5XFAD mouse model for preclinical testing applications: a MODEL-AD study
The ability to investigate therapeutic interventions in animal models of neurodegenerative
diseases depends on extensive characterization of the model (s) being used. There are …
diseases depends on extensive characterization of the model (s) being used. There are …
Hierarchical organization of cortical and thalamic connectivity
The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …
densely interconnected in complex ways, and for which generalizable principles of …
Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
K De Vlaminck, H Van Hove, D Kancheva, I Scheyltjens… - Immunity, 2022 - cell.com
Microglia and border-associated macrophages (BAMs) are brain-resident self-renewing
cells. Here, we examined the fate of microglia, BAMs, and recruited macrophages upon …
cells. Here, we examined the fate of microglia, BAMs, and recruited macrophages upon …
[HTML][HTML] Cellular anatomy of the mouse primary motor cortex
An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …
Genetic dissection of the glutamatergic neuron system in cerebral cortex
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
Map** of brain activity by automated volume analysis of immediate early genes
Understanding how neural information is processed in physiological and pathological states
would benefit from precise detection, localization, and quantification of the activity of all …
would benefit from precise detection, localization, and quantification of the activity of all …
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
Pericytes are perivascular mural cells of brain capillaries. They are positioned centrally in
the neurovascular unit between endothelial cells, astrocytes and neurons. This position …
the neurovascular unit between endothelial cells, astrocytes and neurons. This position …