The role of oxidative stress in anxiety disorder: cause or consequence?

AG Fedoce, F Ferreira, RG Bota… - Free radical …, 2018 - Taylor & Francis
Anxiety disorders are the most common mental illness in the USA affecting 18% of the
population. The cause (s) of anxiety disorders is/are not completely clear, and research in …

Renin-angiotensin system: The underlying mechanisms and promising therapeutical target for depression and anxiety

S Gong, F Deng - Frontiers in Immunology, 2023 - frontiersin.org
Emotional disorders, including depression and anxiety, contribute considerably to morbidity
across the world. Depression is a serious condition and is projected to be the top contributor …

A pontomesencephalic PACAPergic pathway underlying panic-like behavioral and somatic symptoms in mice

SJ Kang, JH Kim, DI Kim, BZ Roberts, S Han - Nature Neuroscience, 2024 - nature.com
Panic disorder is characterized by uncontrollable fear accompanied by somatic symptoms
that distinguish it from other anxiety disorders. Neural mechanisms underlying these unique …

Input-specific synaptic location and function of the α5 GABAA receptor subunit in the mouse CA1 hippocampal neurons

E Magnin, R Francavilla, S Amalyan… - Journal of …, 2019 - Soc Neuroscience
Hippocampus-dependent learning processes are coordinated via a large diversity of
GABAergic inhibitory mechanisms. The α5 subunit-containing GABA A receptor (α5-GABA …

[HTML][HTML] Involvement of oxidative stress and mitochondrial mechanisms in air pollution-related neurobiological impairments

A Salvi, H Liu, S Salim - Neurobiology of stress, 2020 - Elsevier
Background Vehicle exhaust emissions are known to be significant contributors to physical
and psychological stress. Vehicle exhaust-induced stress and associated respiratory and …

Targeting the renin angiotensin system for the treatment of anxiety and depression

S Chrissobolis, AN Luu, RA Waldschmidt… - Pharmacology …, 2020 - Elsevier
Emotional disorders like anxiety and depression are responsible for considerable morbidity
and mortality all over the world. Several antidepressant and anxiolytic medications are …

Behavioral and cognitive impact of early life stress: Insights from an animal model

H Liu, F Atrooz, A Salvi, S Salim - Progress in Neuro-Psychopharmacology …, 2017 - Elsevier
Background Children subjected to traumatic events during childhood are reported to exhibit
behavioral and cognitive deficits later in life, often leading to post-traumatic stress disorder …

Stress, psychiatric disorders, molecular targets, and more

F Atrooz, H Liu, S Salim - Progress in molecular biology and translational …, 2019 - Elsevier
Mental health is central to normal health outcomes. A widely accepted theory is that chronic
persistent stress during adulthood as well as during early life triggers onset of …

[PDF][PDF] Characterization and biological effects of Hypericum extracts on experimentally-induced-anxiety, oxidative stress and inflammation in rats.

AC Sevastre-Berghian, VA Toma, B Sevastre… - Journal of Physiology …, 2018 - jpp.krakow.pl
Anxiety disorders can associate with oxidative stress and immune system alterations. Our
study aimed to chemically analyze Hypericum maculatum (HM) and Hypericum perforatum …

[HTML][HTML] Prophylactic effect of physical exercise on Aβ1–40-induced depressive-like behavior: Role of BDNF, mTOR signaling, cell proliferation and survival in the …

JM Rosa, FL Pazini, G Olescowicz, A Camargo… - Progress in Neuro …, 2019 - Elsevier
Alzheimer's disease (AD) is characterized by progressive cognitive impairments as well as
non-cognitive symptoms such as depressed mood. Physical exercise has been proposed as …