Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …

Abstract 3D-printed composite scaffolds have emerged as an alternative to deal with existing
limitations when facing bone reconstruction. The aim of the study was to systematically …

Cartilage, especially articular cartilage, is a unique connective tissue consisting of
chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in …

This study details the design, fabrication, clinical trials' evaluation, and analysis after the
clinical application of 3D-printed bone reconstruction implants made of nHAp@ PLDLLA …

Polylactic acid (PLA) and hydroxyapatite (HA) composite scaffolds have been widely studied
for applications in bone tissue engineering (BTE) due to their bioactive and biocompatible …

In the current research previously developed composites composed from poly (l-
lactide)(PLLA) and nano-hydroxyapatite (10 wt% nHAp/PLLA) were functionalized with …

MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …

Recent reports imply that drug delivery approaches aimed to modulate the phenotypic and
functional switching of macrophages towards anti-inflammatory (M2) phenotypes have a …

Purpose Osteoporosis results in a severe decrease in the life quality of many people
worldwide. The latest data shows that the number of osteoporotic fractures is becoming an …

In order to improve the interfacial bonding between hydroxyapatite (HAP) and poly-l-lactic
acid (PLLA), 2-Carboxyethylphosphonic acid (CEPA), a phosphonic acid coupling agent …