PI3K/AKT/mTOR signaling pathway in breast cancer: from molecular landscape to clinical aspects

D Miricescu, A Totan, II Stanescu-Spinu… - International journal of …, 2020 - mdpi.com
Breast cancer is a serious health problem worldwide, representing the second cause of
death through malignancies among women in developed countries. Population …

Breast cancer risk factors

M Kamińska, T Ciszewski, K Łopacka-Szatan… - Menopause Review …, 2015 - termedia.pl
Breast cancer is the most frequently diagnosed neoplastic disease in women around
menopause often leading to a significant reduction of these women's ability to function …

Adiposity and cancer risk: new mechanistic insights from epidemiology

AG Renehan, M Zwahlen, M Egger - Nature Reviews Cancer, 2015 - nature.com
Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for
many common adult cancers. Over the past decade, epidemiological data have shown that …

Association of body mass index and age with subsequent breast cancer risk in premenopausal women

MJ Schoemaker, HB Nichols, LB Wright… - JAMA …, 2018 - jamanetwork.com
Importance The association between increasing body mass index (BMI; calculated as weight
in kilograms divided by height in meters squared) and risk of breast cancer is unique in …

World Cancer Research Fund International: Continuous Update Project—systematic literature review and meta-analysis of observational cohort studies on physical …

DSM Chan, L Abar, M Cariolou, N Nanu… - Cancer causes & …, 2019 - Springer
Purpose The purpose of the present study was to systematically review the complex
associations between energy balance-related factors and breast cancer risk, for which …

Estrogen metabolism and breast cancer

H Samavat, MS Kurzer - Cancer letters, 2015 - Elsevier
There is currently accumulating evidence that endogenous estrogens play a critical role in
the development of breast cancer. Estrogens and their metabolites have been studied in …

[HTML][HTML] Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies

E Hormones, Breast Cancer Collaborative Group - The lancet oncology, 2013 - Elsevier
Background Associations between circulating concentrations of oestrogens, progesterone,
and androgens with breast cancer and related risk factors in premenopausal women are not …

[HTML][HTML] Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

TE Hormones, Breast Cancer Collaborative Group - The lancet oncology, 2010 - Elsevier
BACKGROUND: Insulin-like growth factor 1 (IGF1) stimulates mitosis and inhibits apoptosis.
Some published results have shown an association between circulating IGF1 and breast …

Diabetes mellitus and risk of breast cancer: a meta‐analysis

SC Larsson, CS Mantzoros… - International journal of …, 2007 - Wiley Online Library
Diabetes mellitus has been associated with an increased risk of several types of cancers,
but its relationship with breast cancer remains unclear. We conducted a meta‐analysis of …

Cancer and fertility preservation: international recommendations from an expert meeting

M Lambertini, L Del Mastro, MC Pescio, CY Andersen… - BMC medicine, 2016 - Springer
In the last years, thanks to the improvement in the prognosis of cancer patients, a growing
attention has been given to the fertility issues. International guidelines on fertility …