Epilepsy in adults

RD Thijs, R Surges, TJ O'Brien, JW Sander - The lancet, 2019 - thelancet.com
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Autoimmune encephalitis: clinical spectrum and management

CE Uy, S Binks, SR Irani - Practical neurology, 2021 - pn.bmj.com
Autoimmune encephalitis defines brain inflammation caused by a misdirected immune
response against self-antigens expressed in the central nervous system. It comprises a …

Myelin oligodendrocyte glycoprotein antibodies in neurological disease

M Reindl, P Waters - Nature Reviews Neurology, 2019 - nature.com
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

Epilepsy in older people

A Sen, N Jette, M Husain, JW Sander - The Lancet, 2020 - thelancet.com
Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions

C Steriade, J Britton, RC Dale, A Gadoth, SR Irani… - …, 2020 - Wiley Online Library
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …

Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis

MAAM de Bruijn, A van Sonderen… - Neurology, 2019 - neurology.org
Objective This nationwide cohort study evaluates seizure responses to immunotherapy and
antiepileptic drugs (AEDs) in patients with anti-leucine-rich glioma-inactivated 1 (LGI1), anti …

Progress in diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy

C Bunschoten, BC Jacobs, PYK Van den Bergh… - The Lancet …, 2019 - thelancet.com
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare and
heterogeneous but treatable immune-mediated neuropathy. Nerve conduction studies are …

Origins and immunopathogenesis of autoimmune central nervous system disorders

S Ramanathan, F Brilot, SR Irani, RC Dale - Nature Reviews Neurology, 2023 - nature.com
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Autoimmune seizures and epilepsy

C Geis, J Planagumà, M Carreño, F Graus… - The Journal of clinical …, 2019 - jci.org
The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …

LGI1 antibody encephalitis: acute treatment comparisons and outcome

A Rodriguez, CJ Klein, E Sechi, E Alden… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective To compare acute treatment responses and long-term outcome in leucine-rich
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …