Disturbance of the circadian system in shift work and its health impact

DB Boivin, P Boudreau… - Journal of biological …, 2022 - journals.sagepub.com
The various non-standard schedules required of shift workers force abrupt changes in the
timing of sleep and light-dark exposure. These changes result in disturbances of the …

Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Non-coding RNAs: novel players in insulin resistance and related diseases

C Formichi, L Nigi, GE Grieco, C Maccora… - International Journal of …, 2021 - mdpi.com
The rising prevalence of metabolic diseases related to insulin resistance (IR) have stressed
the urgent need of accurate and applicable tools for early diagnosis and treatment. In the …

The circadian clock has roles in mesenchymal stem cell fate decision

W Gao, R Li, M Ye, L Zhang, J Zheng, Y Yang… - Stem Cell Research & …, 2022 - Springer
The circadian clock refers to the intrinsic biological rhythms of physiological functions and
behaviours. It synergises with the solar cycle and has profound effects on normal …

Estrogen-mediated mitigation of cardiac oxidative stress in ovariectomized rats is associated with upregulated cardiac circadian clock Per2 and heart-specific miRNAs

SA Ahmed, B Zhang, AA Abdel-Rahman - Life Sciences, 2023 - Elsevier
Aim Estrogen (E2) confers cardioprotection in premenopausal women and in models of
menopause and its effects, mostly studied in female reproductive organs, vary on a circadian …

The epigenetic mechanism of metabolic risk in bipolar disorder

K Huang, S Li, M Yang, Z Teng, B Xu, B Wang… - Obesity …, 2024 - Wiley Online Library
Bipolar disorder (BD) is a complex and severe mental illness that causes significant
suffering to patients. In addition to the burden of depressive and manic symptoms, patients …

Circadian system microRNAs–Role in the development of cardiovascular diseases

I Škrlec - Advances in Protein Chemistry and Structural Biology, 2023 - Elsevier
Circadian rhythm regulates numerous physiological processes, and disruption of the
circadian clock can lead to cardiovascular disease. Cardiovascular disease is the leading …

Estrogen replacement restores period 2–mediated inhibition of ferroptosis and mitigates cardiac dysfunction in estrogen-deficient rats

SA Ahmed, AA Abdel-Rahman - The Journal of Pharmacology and …, 2025 - Elsevier
The ovarian hormone 17β-estradiol (E2) confers cardioprotection via upregulating cardiac
circadian rhythm period 2 (Per2) and is associated cardioprotective microRNA (miRNAs) …

Differentially Expressed Functional LncRNAs in human subjects with metabolic syndrome reflect a competing endogenous RNA network in circulating extracellular …

Y Li, Y Meng, Y Liu, AJ Van Wijnen, A Eirin… - Frontiers in molecular …, 2021 - frontiersin.org
Metabolic syndrome (MetS), a collective cluster of disease risk factors that include
dyslipidemia, obesity, inflammation, hypertension, and insulin resistance, affects numerous …