Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
The glycosylation in SARS-CoV-2 and its receptor ACE2
Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3
Great advances have been made in mass spectrometric data interpretation for intact
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
Detecting diagnostic features in MS/MS spectra of post-translationally modified peptides
Post-translational modifications are an area of great interest in mass spectrometry-based
proteomics, with a surge in methods to detect them in recent years. However, post …
proteomics, with a surge in methods to detect them in recent years. However, post …
StrucGP: de novo structural sequencing of site-specific N-glycan on glycoproteins using a modularization strategy
J Shen, L Jia, L Dang, Y Su, J Zhang, Y Xu, B Zhu… - Nature …, 2021 - nature.com
Precision map** of glycans at structural and site-specific level is still one of the most
challenging tasks in the glycobiology field. Here, we describe a modularization strategy for …
challenging tasks in the glycobiology field. Here, we describe a modularization strategy for …
Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis
Glycoproteomics is a powerful yet analytically challenging research tool. Software packages
aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but …
aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but …
Glyco-Decipher enables glycan database-independent peptide matching and in-depth characterization of site-specific N-glycosylation
Z Fang, H Qin, J Mao, Z Wang, N Zhang… - Nature …, 2022 - nature.com
Glycopeptides with unusual glycans or poor peptide backbone fragmentation in tandem
mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and …
mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and …
Glycopeptide database search and de novo sequencing with PEAKS GlycanFinder enable highly sensitive glycoproteomics
Here we present GlycanFinder, a database search and de novo sequencing tool for the
analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates …
analysis of intact glycopeptides from mass spectrometry data. GlycanFinder integrates …
Emerging roles of O-glycosylation in regulating protein aggregation, phase separation, and functions
Protein O-glycosylation is widely identified in various proteins involved in diverse biological
processes. Recent studies have demonstrated that O-glycosylation plays crucial and …
processes. Recent studies have demonstrated that O-glycosylation plays crucial and …