Epigenetic clocks are age predictors that use machine-learning models trained on DNA CpG
methylation values to predict chronological or biological age. Increases in predicted …

Acquired and congenital melanocytic naevi are common benign neoplasms. Understanding
their biology and genetics will help clinicians and pathologists correctly diagnose …

Background Cellular compositions of solid tumor microenvironments are heterogeneous,
varying across patients and tumor types. High-resolution profiling of the tumor …

Introduction The human brain comprises heterogeneous cell types whose composition can
be altered with physiological and pathological conditions. New approaches to discern the …

Epigenetic clocks are age predictors that use machine-learning models trained on DNA CpG
methylation values to predict chronological or biological age. Increases in predicted …

Aging is a significant risk factor for various human disorders, and DNA methylation clocks
have emerged as powerful tools for estimating biological age and predicting health‐related …

Epigenetic aging clocks are computational models that predict age using DNA methylation
information. Initially, first-generation clocks were developed to make predictions using CpGs …

One of the main challenges of current research on aging is to identify the complex
epigenetic mechanisms involved in the acquisition of the cellular senescent phenotype …

Early detection of melanoma is critical to good patient outcomes, but we still know little about
the mechanisms of early melanoma development. Normal epidermis has many of the …

Dysplastic nevi represent one of the least agreed-upon entities in dermatopathology despite
the existence of established criteria. This study explores preferentially expressed antigen in …