Light sheet fluorescence microscopy
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …
A guide to light-sheet fluorescence microscopy for multiscale imaging
RM Power, J Huisken - Nature methods, 2017 - nature.com
The impact of light-sheet fluorescence microscopy (LSFM) is visible in fields as diverse as
developmental and cell biology, anatomical science, biophysics and neuroscience …
developmental and cell biology, anatomical science, biophysics and neuroscience …
Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens
For the 1.7 million patients per year in the US who receive a new cancer diagnosis,
treatment decisions are largely based on histopathological specimen examinations …
treatment decisions are largely based on histopathological specimen examinations …
Tissue clearing of both hard and soft tissue organs with the PEGASOS method
Tissue clearing technique enables visualization of opaque organs and tissues in 3-
dimensions (3-D) by turning tissue transparent. Current tissue clearing methods are …
dimensions (3-D) by turning tissue transparent. Current tissue clearing methods are …
Whole-brain profiling of cells and circuits in mammals by tissue clearing and light-sheet microscopy
Tissue clearing and light-sheet microscopy have a 100-year-plus history, yet these fields
have been combined only recently to facilitate novel experiments and measurements in …
have been combined only recently to facilitate novel experiments and measurements in …
[HTML][HTML] Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity
G Lazzari, V Nicolas, M Matsusaki, M Akashi… - Acta biomaterialia, 2018 - Elsevier
The preclinical drug screening of pancreatic cancer treatments suffers from the absence of
appropriate models capable to reproduce in vitro the heterogeneous tumor …
appropriate models capable to reproduce in vitro the heterogeneous tumor …
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution
We present cleared-tissue axially swept light-sheet microscopy (ctASLM), which enables
isotropic, subcellular resolution imaging with high optical sectioning capability and a large …
isotropic, subcellular resolution imaging with high optical sectioning capability and a large …
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples
Light-sheet fluorescence microscopy (LSFM) is a widely used technique for imaging cleared
tissue and living samples. However, high-performance LSFM systems are typically …
tissue and living samples. However, high-performance LSFM systems are typically …
Light-sheet microscopy and its potential for understanding developmental processes
The ability to visualize and quantitatively measure dynamic biological processes in vivo and
at high spatiotemporal resolution is of fundamental importance to experimental …
at high spatiotemporal resolution is of fundamental importance to experimental …
Tutorial: practical considerations for tissue clearing and imaging
Tissue clearing has become a powerful technique for studying anatomy and morphology at
scales ranging from entire organisms to subcellular features. With the recent proliferation of …
scales ranging from entire organisms to subcellular features. With the recent proliferation of …