A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

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A fundamental question in neuroscience is how entire neural circuits generate behaviour
and adapt it to changes in sensory feedback. Here we use two-photon calcium imaging to …

When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrou** between attempts. It is …

The internal brain dynamics that link sensation and action are arguably better studied during
natural animal behaviors. Here, we report on a novel volume imaging and 3D tracking …

Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

The complex neuronal circuitry of the brain develops from limited information contained in
the genome. After the genetic code instructs the birth of neurons, the emergence of brain …

Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting
additional roles of this cell population. The zebrafish optic tectum contains OPCs in regions …

Motor systems must continuously adapt their output to maintain a desired trajectory. While
the spinal circuits underlying rhythmic locomotion are well described, little is known about …

Vertebrate locomotion at different speeds is driven by descending excitatory connections to
central pattern generators in the spinal cord. To investigate how these inputs determine …