[HTML][HTML] ALPPS: challenging the concept of unresectability–a systematic review

KA Bertens, J Hawel, K Lung, S Buac… - International Journal of …, 2015 - Elsevier
Introduction: Hepatic resection for malignancy is limited by the amount of liver parenchyma
left behind. As a result, two-staged hepatectomy and portal vein occlusion (PVO) have …

Early survival and safety of ALPPS: first report of the International ALPPS Registry

E Schadde, V Ardiles, R Robles-Campos… - Annals of …, 2014 - journals.lww.com
Objectives: To assess safety and outcomes of the novel 2-stage hepatectomy, Associating
Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS), using an …

ALPPS: from human to mice highlighting accelerated and novel mechanisms of liver regeneration

A Schlegel, M Lesurtel, E Melloul, P Limani… - Annals of …, 2014 - journals.lww.com
Objectives: To develop a reproducible animal model mimicking a novel 2-staged
hepatectomy (ALPPS: Associating Liver Partition and Portal Vein Ligation for Staged …

An updated systematic review of the evolution of ALPPS and evaluation of its advantages and disadvantages in accordance with current evidence

YL Cai, PP Song, W Tang, NS Cheng - Medicine, 2016 - journals.lww.com
The main obstacle to achieving an R0 resection after a major hepatectomy is inability to
preserve an adequate future liver remnant (FLR) to avoid postoperative liver failure (PLF) …

ALPPS for patients with colorectal liver metastases: effective liver hypertrophy, but early tumor recurrence

KJ Oldhafer, M Donati, RM Jenner… - World journal of …, 2014 - Wiley Online Library
Background Associating liver partition and portal vein ligation for staged hepatectomy
(ALPPS) is a promising method to increase resectability rates of liver tumors. Little has been …

Laparoscopic microwave ablation and portal vein ligation for staged hepatectomy (LAPS): a minimally invasive first-step approach

E Gringeri, R Boetto, FE D'Amico, D Bassi… - Annals of surgery, 2015 - journals.lww.com
We read with great interest the article by Dr Schnitzbauer et al, 1 describing a multicenter
study on “ALPPS”(Associating Liver Partition and Portal vein ligation for Staged …

Hedgehog pathway mediates early acceleration of liver regeneration induced by a novel two-staged hepatectomy in mice

M Langiewicz, A Schlegel, E Saponara, M Linecker… - Journal of …, 2017 - Elsevier
Background & Aims ALPPS, a novel two-staged approach for the surgical removal of
large/multiple liver tumors, combines portal vein ligation (PVL) with parenchymal …

JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice

M Langiewicz, R Graf, B Humar, PA Clavien - Journal of hepatology, 2018 - Elsevier
Background & Aims To improve outcomes of two-staged hepatectomies for large/multiple
liver tumors, portal vein ligation (PVL) has been combined with parenchymal transection …

Technical modifications and outcomes after Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) for primary liver malignancies: A …

E Baili, DI Tsilimigras, D Moris, K Sahara, TM Pawlik - Surgical Oncology, 2020 - Elsevier
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
represents a novel surgical technique which provides rapid and effective liver regeneration …

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in colorectal liver metastases: review of the literature

D Coco, S Leanza - Clinical and Experimental Hepatology, 2021 - termedia.pl
The liver is considered as one of the most common sites of metastasis and a key
determining factor of survival in patients with isolated colorectal liver metastasis (CRLM). For …