Quadruplex-forming sequences are widely prevalent in human and other genomes,
including bacterial ones. These sequences are over-represented in eukaryotic telomeres …

Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids;
therefore, CD spectroscopy has been used to study most features of DNA and RNA …

DNA structure can regulate genome function. Four-stranded DNA G-quadruplex (G4)
structures have been implicated in transcriptional regulation; however, previous studies …

A curated library of circular dichroism spectra of 23 G‐quadruplexes of known structure was
built and analyzed. The goal of this study was to use this reference library to develop an …

DNA–protein interactions regulate critical biological processes. Identifying proteins that bind
to specific, functional genomic loci is essential to understand the underlying regulatory …

Abstract G-quadruplexes (G4) are helical structures found in guanine-rich DNA or RNA
sequences. Generally, their formalism is based on a few dozen structures, which can …

Guanine-rich RNA sequences can fold into four-stranded structures, termed G-quadruplexes
(G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated …

The G-quadruplex is an alternative DNA structural motif that is considered to be functionally
important in the mammalian genome for transcriptional regulation, DNA replication and …

Nucleic acids bear the genetic information and participate in its expression and evolution
during replication, repair, recombination, transcription, and translation. These phenomena …

Visualization of DNA and RNA quadruplex formation in human cells was demonstrated
recently with different quadruplex-specific antibodies. Despite the significant interest in these …