Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022 - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: a mechanistic review

A Strzelak, A Ratajczak, A Adamiec… - International journal of …, 2018 - mdpi.com
Many studies have been undertaken to reveal how tobacco smoke skews immune
responses contributing to the development of chronic obstructive pulmonary disease …

Beyond infection-Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders

SD Bilbo, CL Block, JL Bolton, R Hanamsagar… - Experimental …, 2018 - Elsevier
Immune molecules such as cytokines and chemokines and the cells that produce them
within the brain, notably microglia, are critical for normal brain development. This recognition …

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

H Renz, P Brandtzaeg, M Hornef - Nature Reviews Immunology, 2012 - nature.com
The mucosal surfaces of the gut and airways have important barrier functions and regulate
the induction of immunological tolerance. The rapidly increasing incidence of chronic …

Early life origins of chronic obstructive pulmonary disease

C Svanes, J Sunyer, E Plana, S Dharmage, J Heinrich… - Thorax, 2010 - thorax.bmj.com
Background: Early life development may influence subsequent respiratory morbidity. The
impact of factors determined in childhood on adult lung function, decline in lung function and …

Poor airway function in early infancy and lung function by age 22 years: a non-selective longitudinal cohort study

DA Stern, WJ Morgan, AL Wright, S Guerra… - The Lancet, 2007 - thelancet.com
Background Together with smoking, the lung function attained in early adulthood is one of
the strongest predictors of chronic obstructive pulmonary disease. We aimed to investigate …

Long-term consequences of fetal and neonatal nicotine exposure: a critical review

JE Bruin, HC Gerstein, AC Holloway - Toxicological sciences, 2010 - academic.oup.com
Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and
developmental complications, as well as an increased risk of adverse health consequences …

Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children

FD Gilliland, YF Li, JM Peters - American journal of respiratory and …, 2001 - atsjournals.org
The effects of maternal smoking during pregnancy and childhood environmental tobacco
smoke (ETS) exposure on asthma and wheezing were investigated in 5,762 school-aged …

COPD: balancing oxidants and antioxidants

BM Fischer, JA Voynow, AJ Ghio - International journal of chronic …, 2015 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic illnesses
in the world. The disease encompasses emphysema, chronic bronchitis, and small airway …

Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease

T Yoshida, RM Tuder - Physiological reviews, 2007 - journals.physiology.org
Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …