Exosomes: key players in cancer and potential therapeutic strategy
J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Tumour cells evade immune surveillance by upregulating the surface expression of
programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) …
programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) …
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance
The tumor microenvironment represents a complex network, in which tumor cells not only
communicate with each other but also with stromal and immune cells. Current research has …
communicate with each other but also with stromal and immune cells. Current research has …
Extracellular vesicles in cancer: cell-to-cell mediators of metastasis
Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant …
communication between tumor cells and stromal cells in local and distant …
Exosome-based cell-cell communication in the tumor microenvironment
J Maia, S Caja, MC Strano Moraes, N Couto… - Frontiers in cell and …, 2018 - frontiersin.org
Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …
communication between transformed and non-transformed cells. The milieu created by …
Engineering exosomes as refined biological nanoplatforms for drug delivery
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important
mediators of long distance intercellular communication and are involved in a diverse range …
mediators of long distance intercellular communication and are involved in a diverse range …
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1)
leads to cancer immune evasion via inhibition of T cell function. One of the defining …
leads to cancer immune evasion via inhibition of T cell function. One of the defining …
[HTML][HTML] Design strategies and application progress of therapeutic exosomes
C Liu, C Su - Theranostics, 2019 - ncbi.nlm.nih.gov
Exosomes have great potential to be drug delivery vehicles due to their natural material
transportation properties, intrinsic long-term circulatory capability, and excellent …
transportation properties, intrinsic long-term circulatory capability, and excellent …
[HTML][HTML] The biology, function, and applications of exosomes in cancer
J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …