The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Angiotensin‐converting enzyme 2 (ACE2) shares some homology with angiotensin‐
converting enzyme (ACE) but is not inhibited by ACE inhibitors. The main role of ACE2 is the …

Rationale: The renin–angiotensin system (RAS) is a key regulator of the cardiovascular
system, electrolyte, and water balance. Here, we report identification and characterization of …

Santos Cardiovascular Actions of Angiotensin-(1–7) 1139 in caveolin 3 expression and a
decrease in heat shock protein 90. 28 These 2 alterations may lead to a decrease in eNOS …

Skeletal muscle is a tissue that shows the most plasticity in the body; it can change in
response to physiological and pathological stimuli. Among the diseases that affect skeletal …

Background and Purpose Inflammation plays a key role in atherosclerosis. The protective
role of angiotensin 1–7 (Ang‐(1–7)) in vascular pathologies suggested the therapeutic use …

The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as
well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT1 …

Abstract Angiotensin converting enzyme-2 (ACE2) is a multifunctional transmembrane
protein recently recognised as the entry receptor of the virus causing COVID-19. In the renin …

BACKGROUND AND PURPOSE Angiotensin‐(1‐7)[Ang‐(1‐7)] has anti‐inflammatory
effects in peripheral organs, but its effects in ischaemic stroke are unclear as yet. We …

The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors of the protective
arm of the renin–angiotensin system. They mediate strikingly similar actions. Moreover, in …