Cutaneous leishmaniasis: a 2022 updated narrative review into diagnosis and management developments

HJC de Vries, HD Schallig - American journal of clinical dermatology, 2022 - Springer
This review is an update of an earlier narrative review published in 2015 on developments
in the clinical management of cutaneous leishmaniasis (CL) including diagnosis, treatment …

Cyclobutanes in small‐molecule drug candidates

MR van der Kolk, MACH Janssen, FPJT Rutjes… - …, 2022 - Wiley Online Library
Cyclobutanes are increasingly used in medicinal chemistry in the search for relevant
biological properties. Important characteristics of the cyclobutane ring include its unique …

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

A Ponte-Sucre, F Gamarro, JC Dujardin… - PLoS neglected …, 2017 - journals.plos.org
Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently
needed on a global basis because treatment failure is an increasing problem. Drug …

Leishmaniasis in humans: drug or vaccine therapy?

M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

MC Field, D Horn, AH Fairlamb… - Nature Reviews …, 2017 - nature.com
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …

Joint deep autoencoder and subgraph augmentation for inferring microbial responses to drugs

Z Zhou, L Zhuo, X Fu, Q Zou - Briefings in Bioinformatics, 2024 - academic.oup.com
Exploring microbial stress responses to drugs is crucial for the advancement of new
therapeutic methods. While current artificial intelligence methodologies have expedited our …

Cutaneous leishmaniasis: recent developments in diagnosis and management

HJC de Vries, SH Reedijk, HDFH Schallig - American journal of clinical …, 2015 - Springer
This review focuses on recent developments in the diagnosis, treatment, management, and
strategies for the prevention and control of cutaneous leishmaniasis (CL) caused by both …

An overview of drug resistance in protozoal diseases

R Capela, R Moreira, F Lopes - International journal of molecular …, 2019 - mdpi.com
Protozoan diseases continue to be a worldwide social and economic health problem.
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …

[HTML][HTML] Worldwide risk factors in leishmaniasis

A Oryan, M Akbari - Asian Pacific journal of tropical medicine, 2016 - Elsevier
Recently, vector-borne parasitic diseases such as leishmaniasis have been emerged or re-
emerged in many geographical areas and resulted in global health and economic concerns …

[HTML][HTML] Antimony toxicity

S Sundar, J Chakravarty - … journal of environmental research and public …, 2010 - mdpi.com
Antimony toxicity occurs either due to occupational exposure or during therapy.
Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on …