Since their first observation, understanding the biology of extracellular vesicles (EV) has
been an important and challenging field of study. They play a key role in the intercellular …

Abstract Proteins, RNA, DNA, lipids, and carbohydrates are only some of the molecular
components found in exosomes released by tumor cells. They play an essential role in …

Reserpine is an effective drug for the clinical treatment of hypertension. It also induces
Parkinson's disease (PD)-like symptoms in humans and animals possible through the …

Peptidylarginine deiminases (PADs) are a family of calcium-regulated enzymes that are
phylogenetically conserved and cause post-translational deimination/citrullination …

Extracellular vesicles (EVs) are biological nanoparticles of great interest as novel sources of
biomarkers and as drug delivery systems for personalized therapies. The research in the …

Pediatric epilepsy is a neurological condition that causes repeated and unprovoked
seizures and is more common in 1–5-year-old children. Drug resistance has been indicated …

The detection of early molecular mechanisms and potential biomarkers in Parkinson's
disease (PD) remains a challenge. Recent research has pointed to novel roles for post …

Glioblastoma (GBM) is the deadliest brain tumor. Its poor prognosis is due to cell
heterogeneity, invasiveness, and high vascularization that impede an efficient therapeutic …

Among the~ 22,000 human genes, very few remain that have unknown functions. One such
example is suprabasin (SBSN). Originally described as a component of the cornified …

Multiple organs and tissues coordinate to respond to dietary and environmental challenges.
It is interorgan crosstalk that contributes to systemic metabolic homeostasis. The liver and …