Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a
consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a …

Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …

Adjuvant chemotherapy based on 5-fluorouracil (5-FU), such as FOLFOX, is suggested as a
treatment for gastrointestinal cancer. Yet, intestinal damage continues to be a prevalent side …

Breast cancer is one of the most common malignancies in women, and exhibits high
metastasis, recurrence and fatality rates. Novel therapies for breast cancer are constantly …

Aim Liver cirrhosis is the result of a vicious cycle of both chronic oxidative stress and
inflammation. NADPH oxidase-4 (NOX4) and its companion, NOD-like receptor protein 3 …

Aims Ehrlich ascites carcinoma and its subcutaneous inoculated solid tumour form (SEC)
are reliable models for chemotherapeutic molecular targets exploration. Novel …

The rewiring of cellular metabolism is a defining characteristic of cancer, as tumor cells
adapt to acquire essential nutrients from a nutrient-poor environment to sustain their viability …

Cancer, which is a leading cause of deaths around the world, is characterized by genetic
mutations and epigenetic changes. Baicalin and its aglycone baicalein, the major bioactive …

The aim of this study was to investigate the effects of baicalin, chrysin and their combinations
against emamectin benzoate-induced toxicity in rats. For this purpose, sixty four rats were …

Objectives Baicalin is a promising anticancer nutraceutical compound, but its application is
hindered by its low water solubility and bioavailability, which can be remedied by its …