Deferoxamine B: a natural, excellent and versatile metal chelator

D Bellotti, M Remelli - Molecules, 2021 - mdpi.com
Deferoxamine B is an outstanding molecule which has been widely studied in the past
decade for its ability to bind iron and many other metal ions. The versatility of this metal …

Traversing the coordination chemistry and chemical biology of hydroxamic acids

R Codd - Coordination Chemistry Reviews, 2008 - Elsevier
Hydroxamic acids, RCC (O) N (RN) OH (RC= alkyl/aryl; RN= alkyl/aryl or H), coordinate a
wide variety of transition metal ions predominantly as the monoanionic hydroxamato or …

Assessment of interactions between transition metals and atmospheric organics: Ascorbic acid depletion and hydroxyl radical formation in organic-metal mixtures

M Lin, JZ Yu - Environmental Science & Technology, 2020 - ACS Publications
Excessive oxidative stress has been recognized as an important cause of the adverse health
effects associated with exposure to ambient particulate matter (PM). Transition metals …

A comparison between the chelating properties of some dihydroxamic acids, desferrioxamine B and acetohydroxamic acid

E Farkas, ÉA Enyedy, H Csóka - Polyhedron, 1999 - Elsevier
The complexes of hexanedioic acid bis (3-hydroxycarbamoyl-methyl) amide (Dha1) and
hexanedioic acid bis (3-hydroxycarbamoyl-propyl) amide (Dha2) with cobalt (II), nickel (II) …

Oxidative mobilization of cerium and uranium and enhanced release of “immobile” high field strength elements from igneous rocks in the presence of the biogenic …

D Kraemer, S Kopf, M Bau - Geochimica et Cosmochimica Acta, 2015 - Elsevier
Polyvalent trace elements such as the high field strength elements (HFSE) are commonly
considered rather immobile during low-temperature water–rock interaction. Hence, they …

A friendly complexing agent for spectrophotometric determination of total iron

VM Nurchi, R Cappai, N Spano, G Sanna - Molecules, 2021 - mdpi.com
Iron, one of the most common metals in the environment, plays a fundamental role in many
biological as well as biogeochemical processes, which determine its availability in different …

The anticancer agent di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of …

E Gutierrez, DR Richardson, PJ Jansson - Journal of Biological Chemistry, 2014 - ASBMB
Autophagy functions as a survival mechanism during cellular stress and contributes to
resistance against anticancer agents. The selective antitumor and antimetastatic chelator di …

Highly chelating stellate mesoporous silica nanoparticles for specific iron removal from biological media

P Duenas-Ramirez, C Bertagnolli, R Müller… - Journal of Colloid and …, 2020 - Elsevier
In this work, the design of a new generation of functionalized large pore silica nanoparticles
is addressed for the specific removal of iron from biological environments. Herein …

A speciation study on the perturbing effects of iron chelators on the homeostasis of essential metal ions

G Crisponi, VM Nurchi, M Crespo-Alonso, G Sanna… - PloS one, 2015 - journals.plos.org
A number of reports have appeared in literature calling attention to the depletion of essential
metal ions during chelation therapy on β-thalassaemia patients. We present a speciation …

Chemical features of in use and in progress chelators for iron overload

VM Nurchi, G Crisponi, JI Lachowicz, S Medici… - Journal of trace …, 2016 - Elsevier
An excessive amount of iron may become extremely toxic both for its ability to generate
reactive oxygen species, and for the lack of regulatory mechanisms for iron excretion in …