Computational chemistry approach based on density functional theory (DFT) was utilized to
investigate the interaction, adsorption behaviour, electronic and structural properties of …

Bacterial infections have always been a major threat to public health, and the development
of effective antibacterial substances from natural polymers is crucial. 2-Aminoisonicotinic …

Recently, the co-crystallization of pharmaceutical drugs is gaining consideration because it
is an environmentally friendly and potentially effective technique to improve the solubility …

Despite having a wide range of therapeutic advantages, glycyrrhizin (GL) has few
commercial applications due to its poor aqueous solubility. In this study, we combined the …

With the continuous development of the medical field, drugs for cancer treatment are
emerging in an endless stream. Many kinds of natural plant, animal, and microbial extracts …

Irbesartan (IBS), a common drug to treat hypertension, has poor oral bioavailability because
of its limited aqueous solubility. Recently, co-amorphous systems (CAMs) have …

Drug–drug salts are a kind of pharmaceutical multicomponent solid in which the two co-
existing components are active pharmaceutical ingredients (APIs) in their ionized forms. This …

Introduction This current research reports the synthesis and characterization of a cocrystal of
Fluconazole (FLU), a widely used antifungal drug, with a nutraceutical coformer (NCF) that …

Objective: This study was to prepare solid dispersions of lidocaine (Lid) with 5-sulfosalicylic
acid dihydrate (SSA) by freeze-drying (freeze-dried [FD] Lid/SSA= 1/1) and to evaluate their …

For dissolution enhancement of poorly water-soluble APIs, a novel production method for
multi-component solids was proposed by develo** the melt crystallization concept into …