[HTML][HTML] Stress, diet, exercise: common environmental factors and their impact on epigenetic age

F Galkin, O Kovalchuk, D Koldasbayeva… - Ageing Research …, 2023‏ - Elsevier
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …

The impact of life stress on hallmarks of aging and accelerated senescence: connections in sickness and in health

CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023‏ - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

Social ageing: exploring the drivers of late-life changes in social behaviour in mammals

ER Siracusa, JP Higham… - Biology …, 2022‏ - royalsocietypublishing.org
Social interactions help group-living organisms cope with socio-environmental challenges
and are central to survival and reproductive success. Recent research has shown that social …

Behavioural and physiological plasticity in social hierarchies

TM Milewski, W Lee… - … Transactions of the …, 2022‏ - royalsocietypublishing.org
Individuals occupying dominant and subordinate positions in social hierarchies exhibit
divergent behaviours, physiology and neural functioning. Dominant animals express higher …

Social bonds, social status and survival in wild baboons: a tale of two sexes

FA Campos, F Villavicencio… - … of the Royal …, 2020‏ - royalsocietypublishing.org
People who are more socially integrated or have higher socio-economic status live longer.
Recent studies in non-human primates show striking convergences with this human pattern …

The rate of epigenetic drift scales with maximum lifespan across mammals

EM Bertucci-Richter, BB Parrott - Nature Communications, 2023‏ - nature.com
Epigenetic drift or “disorder” increases across the mouse lifespan and is suggested to
underlie epigenetic clock signals. While the role of epigenetic drift in determining maximum …

Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults

F Galkin, K Kochetov, D Koldasbayeva… - Aging (Albany …, 2022‏ - pmc.ncbi.nlm.nih.gov
We have developed a deep learning aging clock using blood test data from the China
Health and Retirement Longitudinal Study, which has a mean absolute error of 5.68 years …

Social and early life determinants of survival from cradle to grave: a case study in wild baboons

J Tung, EC Lange, SC Alberts, EA Archie - Neuroscience & Biobehavioral …, 2023‏ - Elsevier
Field studies of natural mammal populations present powerful opportunities to investigate
the determinants of health and aging using fine-grained observations of known individuals …

Biological clocks as age estimation markers in animals: a systematic review and meta‐analysis

LS Le Clercq, A Kotzé, JP Grobler… - Biological …, 2023‏ - Wiley Online Library
Various biological attributes associated with individual fitness in animals change predictably
over the lifespan of an organism. Therefore, the study of animal ecology and the work of …

Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment

KL Chiou, AR DeCasien, KP Rees, C Testard… - Nature …, 2022‏ - nature.com
Aging is accompanied by a host of social and biological changes that correlate with
behavior, cognitive health and susceptibility to neurodegenerative disease. To understand …