Forging Amides Through Metal‐Catalyzed C–C Coupling with Isocyanates

E Serrano, R Martin - European Journal of Organic Chemistry, 2018 - Wiley Online Library
The natural occurrence of amides and their unique roles in synthetic materials and
biologically active compounds make amide synthesis one of the most routinely performed …

Nickel-Catalyzed Reductive Amidation of Aryl Fluorosulfates with Isocyanates: Synthesis of Amides via C–O Bond Cleavage

GQ Qin, J Wang, XR Cao, XQ Chu, X Zhou… - The Journal of …, 2024 - ACS Publications
With the assistance of nickel as catalyst, 2, 2′-bipyridine (bpy) as ligand, and manganese
as reducing metal, the reductive amidation of isocyanates with readily accessible aryl …

Direct access to chiral secondary amides by copper-catalyzed borylative carboxamidation of vinylarenes with isocyanates

D Fiorito, Y Liu, C Besnard, C Mazet - Journal of the American …, 2019 - ACS Publications
A Cu-catalyzed borylative carboxamidation reaction has been developed using vinylarenes
and isocyanates. Alkynes, branched 1, 3-dienes, and bicyclic alkenes were also found to be …

Copper-catalyzed borylamidation of vinyl arenes with isocyanates

Z Su, Y Feng, R Zou, X Qiu, J Wang… - Chemical …, 2020 - pubs.rsc.org
A copper-catalyzed borylative amidation of vinyl arenes with isocyanates and bis
(pinacolato) diboron has been developed. This new protocol, which can be performed on a …

A practical and general amidation method from isocyanates enabled by flow technology

JD Williams, WJ Kerr, SG Leach… - Angewandte Chemie …, 2018 - Wiley Online Library
The addition of carbon nucleophiles to isocyanates represents a conceptually flexible and
efficient approach to the preparation of amides. This general synthetic strategy has …

Rhodium-catalyzed synthesis of amides from functionalized blocked isocyanates

JS Derasp, AM Beauchemin - ACS Catalysis, 2019 - ACS Publications
Isocyanates are useful building blocks for the synthesis of amides, although their
widespread use has been limited by their high reactivity, which often results in poor …

Stereoselective Formal Hydroamidation of Si-Substituted Arylacetylenes with DIBAL-H and Isocyanates: Synthesis of (E)- and (Z)-α-Silyl-α,β-unsaturated Amides

H Lee, S Cho, Y Lee, B Jung - The Journal of Organic Chemistry, 2020 - ACS Publications
An efficient and stereoselective method for the synthesis of (E)-and (Z)-α-silyl-α, β-
unsaturated amides and its synthetic applications are presented herein. The solvent …

A catalyst-free cross-coupling of isocyanates and triarylboranes for secondary amide synthesis

YW Wu, MX Chen, Y Li, LM Hu, L Zhao, Z Jia… - Organic Chemistry …, 2024 - pubs.rsc.org
Described herein is a distinct protocol for secondary amide formation through a catalyst-free
cross-coupling of isocyanates with triarylboranes. As a practical strategy, this methodology …

Palladium-Mediated CO2 Extrusion Followed by Insertion of Isocyanates for the Synthesis of Benzamides: Translating Fundamental Mechanistic Studies To Develop …

Y Yang, AJ Canty, AI McKay, PS Donnelly… - …, 2020 - ACS Publications
Mechanistic studies of a stoichiometric palladium-mediated ExIn (ExIn= extrusion–insertion)
decarboxylative amidation of aromatic carboxylic acids are presented, providing gas-phase …

Nickel-catalyzed reductive amidation of aryl-triazine ethers

MM Heravi, F Panahi, N Iranpoor - Chemical Communications, 2020 - pubs.rsc.org
Nickel-catalyzed reductive amidation of aryl-triazine ethers - Chemical Communications (RSC
Publishing) DOI:10.1039/C9CC08727C Royal Society of Chemistry View PDF VersionPrevious …