Through a widespread efferent projection system, the locus coeruleus–noradrenergic
system supplies norepinephrine throughout the central nervous system. Initial studies …

The synapsins are a family of neuronal phosphoproteins evolutionarily conserved in
invertebrate and vertebrate organisms. Their best-characterised function is to modulate …

The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and
memory. Here we begin with an overview of the LC-NE system. We then consider how both …

Neuromodulators including acetylcholine, norepinephrine, serotonin, dopamine and a range
of peptides alter the processing characteristics of cortical networks through effects on …

A deficiency in the noradrenergic system of the brain, originating largely from cells in the
locus coeruleus (LC), is theorized to play a critical role in the progression of a family of …

The vagus nerve is an important source of afferent information about visceral states and it
provides input to the locus coeruleus (LC), the major source of norepinephrine (NE) in the …

A group of rats was trained to escape low-intensity shock in a shuttle-box test, while another
group of yoked controls could not escape but was exposed to the same amount and regime …

In normal life, organisms are repeatedly exposed to brief periods of stress, most of which can
be controlled and adequately dealt with. The presently available data indicate that such brief …

The involvement of dopaminergic mechanisms in the induction and maintenance of
posttetanic long-term potentiation (LTP) was investigated on CA1 cells of rat hippocampal …

Behavioral studies indicate that the ability to acquire long-term memories is severely
impaired during sleep. It is unclear, however, why the highly synchronous discharge of …