[HTML][HTML] Recent therapeutic trends and promising targets in triple negative breast cancer
SY Hwang, S Park, Y Kwon - Pharmacology & therapeutics, 2019 - Elsevier
Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …
Circulating proteins as predictive and prognostic biomarkers in breast cancer
Breast cancer (BC) is the most common cancer and among the leading causes of cancer
death in women. It is a heterogeneous group of tumours with numerous morphological and …
death in women. It is a heterogeneous group of tumours with numerous morphological and …
LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesis
Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BC) with the most
aggressive phenotype and poor overall survival. Using bioinformatics tools, we identified …
aggressive phenotype and poor overall survival. Using bioinformatics tools, we identified …
Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling
TGFβ signaling plays crucial role during development and cancer, however the role for
TGFβ signaling in regulating the noncoding part of the human genome in triple negative …
TGFβ signaling in regulating the noncoding part of the human genome in triple negative …
Inhibition of EZH2 catalytic activity selectively targets a metastatic subpopulation in triple-negative breast cancer
Epigenetic changes are increasingly being appreciated as key events in breast cancer
progression. However, breast cancer subtype-specific epigenetic regulation remains poorly …
progression. However, breast cancer subtype-specific epigenetic regulation remains poorly …
Insulin-like growth factor (IGF) axis in cancerogenesis
A Kasprzak, W Kwasniewski, A Adamek… - … Research/Reviews in …, 2017 - Elsevier
Determination of the role of insulin-like growth factor (IGF) family components in
carcinogenesis of several human tumors is based on numerous epidemiological and pre …
carcinogenesis of several human tumors is based on numerous epidemiological and pre …
Design of rhenium compounds in targeted anticancer therapeutics
P Collery, D Desmaele… - Current Pharmaceutical …, 2019 - ingentaconnect.com
Background: Many rhenium (Re) complexes with potential anticancer properties have been
synthesized in the recent years with the aim to overcome the clinical limitations of platinum …
synthesized in the recent years with the aim to overcome the clinical limitations of platinum …
Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer
Background Altered signaling pathways typify breast cancer and serve as direct inputs to
steroid hormone receptor sensors. We previously reported that phospho-Ser134-GR (pS134 …
steroid hormone receptor sensors. We previously reported that phospho-Ser134-GR (pS134 …
Therapeutic potential of thymoquinone in triple-negative breast cancer prevention and progression through the modulation of the tumor microenvironment
To date, the tumor microenvironment (TME) has gained considerable attention in various
areas of cancer research due to its role in driving a loss of immune surveillance and …
areas of cancer research due to its role in driving a loss of immune surveillance and …
Druggable molecular targets for the treatment of triple negative breast cancer
M Nakhjavani, JE Hardingham… - Journal of breast …, 2019 - synapse.koreamed.org
Breast cancer (BC) is still the most common cancer among women worldwide. Amongst the
subtypes of BC, triple negative breast cancer (TNBC) is characterized by deficient …
subtypes of BC, triple negative breast cancer (TNBC) is characterized by deficient …