[HTML][HTML] Electrospinning technologies for the delivery of Biopharmaceuticals: Current status and future trends

S Lian, D Lamprou, M Zhao - International Journal of Pharmaceutics, 2024 - Elsevier
This review provides an in-depth exploration of electrospinning techniques employed to
produce micro-or nanofibres of biopharmaceuticals using polymeric solutions or melts with …

Drug delivery systems for programmed and on-demand release

P Davoodi, LY Lee, Q Xu, V Sunil, Y Sun, S Soh… - Advanced drug delivery …, 2018 - Elsevier
With the advancement in medical science and understanding the importance of
biodistribution and pharmacokinetics of therapeutic agents, modern drug delivery research …

PLGA: a unique polymer for drug delivery

DN Kapoor, A Bhatia, R Kaur, R Sharma… - Therapeutic …, 2015 - Taylor & Francis
Biodegradable polymers have played an important role in the delivery of drugs in a
controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of the extensively …

Drug delivery systems, CNS protection, and the blood brain barrier

RK Upadhyay - BioMed research international, 2014 - Wiley Online Library
Present review highlights various drug delivery systems used for delivery of pharmaceutical
agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic …

The role and mechanisms of gram-negative bacterial outer membrane vesicles in inflammatory diseases

S Chen, Q Lei, X Zou, D Ma - Frontiers in Immunology, 2023 - frontiersin.org
Outer membrane vesicles (OMVs) are spherical, bilayered, and nanosized membrane
vesicles that are secreted from gram-negative bacteria. OMVs play a pivotal role in …

Protein encapsulation by electrospinning and electrospraying

A Moreira, D Lawson, L Onyekuru… - Journal of Controlled …, 2021 - Elsevier
Given the increasing interest in the use of peptide-and protein-based agents in therapeutic
strategies, it is fundamental to develop delivery systems capable of preserving the biological …

Hydrogel based approaches for cardiac tissue engineering

L Saludas, S Pascual-Gil, F Prósper, E Garbayo… - International journal of …, 2017 - Elsevier
Heart failure still represents the leading cause of death worldwide. Novel strategies using
stem cells and growth factors have been investigated for effective cardiac tissue …

The role of midkine in health and disease

EE Neumaier, V Rothhammer… - Frontiers in …, 2023 - frontiersin.org
Midkine (MDK) is a neurotrophic growth factor highly expressed during embryogenesis with
important functions related to growth, proliferation, survival, migration, angiogenesis …

Trends in drug delivery systems for natural bioactive molecules to treat health disorders: the importance of nano-liposomes

RV Cardoso, PR Pereira, CS Freitas, VMF Paschoalin - Pharmaceutics, 2022 - mdpi.com
Drug delivery systems are believed to increase pharmaceutical efficacy and the therapeutic
index by protecting and stabilizing bioactive molecules, such as protein and peptides …

Nanocarrier fabrication and macromolecule drug delivery: challenges and opportunities

V Agrahari, V Agrahari, AK Mitra - Therapeutic delivery, 2016 - Taylor & Francis
Macromolecules (proteins/peptides) have the potential for the development of new
therapeutics. Due to their specific mechanism of action, macromolecules can be …