[HTML][HTML] Redox homeostasis, gut microbiota, and epigenetics in neurodegenerative diseases: A systematic review

C Munteanu, AI Galaction, M Turnea, CD Blendea… - Antioxidants, 2024 - mdpi.com
Neurodegenerative diseases encompass a spectrum of disorders marked by the
progressive degeneration of the structure and function of the nervous system. These …

Histone post-translational modification and heterochromatin alterations in neurodegeneration: revealing novel disease pathways and potential therapeutics

RMA Fisher, MP Torrente - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Alzheimer's disease (AD), Parkinson's disease (PD), Frontotemporal Dementia (FTD), and
Amyotrophic lateral sclerosis (ALS) are complex and fatal neurodegenerative diseases …

[HTML][HTML] Neuro-HIV—New insights into pathogenesis and emerging therapeutic targets

D Sviridov, M Bukrinsky - FASEB journal: official publication of the …, 2023 - ncbi.nlm.nih.gov
HIV-associated neurocognitive disorders (HAND) is a term describing a complex set of
cognitive impairments accompanying HIV infection. Successful antiretroviral therapy (ART) …

[HTML][HTML] Systematic review of what people know about brain health

MA Niechcial, SM Elhag, LM Potter, A Dickson… - Ageing Research …, 2024 - Elsevier
Objectives As we age our cognitive abilities can change. However, the degree of change
experienced can be positively influenced by a range of factors. To understand what the …

Deciphering the Microbial Map and its implications in the therapeutics of Neurodegenerative Disorder

S Vashishth, RK Ambasta, P Kumar - Ageing Research Reviews, 2024 - Elsevier
Every facet of biological anthropology, including development, ageing, diseases, and even
health maintenance, is influenced by gut microbiota's significant genetic and metabolic …

[HTML][HTML] Epigenetic Mechanisms in Aging: Extrinsic Factors and Gut Microbiome

A Borrego-Ruiz, JJ Borrego - Genes, 2024 - mdpi.com
Background/Objectives: Aging is a natural physiological process involving biological and
genetic pathways. Growing evidence suggests that alterations in the epigenome during …

Whole-Genome Bisulfite Sequencing Protocol for the Analysis of Genome-Wide DNA Methylation and Hydroxymethylation Patterns at Single-Nucleotide Resolution

D Derbala, A Garnier, E Bonnet, JF Deleuze… - … Editing: Methods and …, 2024 - Springer
The analysis of genome-wide epigenomic alterations including DNA methylation and
hydroxymethylation has become a subject of intensive research for many biological and …

Unlocking the epigenetic symphony: histone acetylation's impact on neurobehavioral change in neurodegenerative disorders

BS Basavarajappa, S Subbanna - Epigenomics, 2024 - Taylor & Francis
Recent genomics and epigenetic advances have empowered the exploration of DNA/RNA
methylation and histone modifications crucial for gene expression in response to stress …

[HTML][HTML] A lifetime perspective on risk factors for cognitive decline with a special focus on early events

HG Kuhn, S Skau, J Nyberg - Cerebral Circulation-Cognition and Behavior, 2024 - Elsevier
Both Alzheimer's disease and vascular dementia are the result of disease processes that
typically develop over several decades. Population studies have estimated that more than …

Neurological Disorders and Challenges in Their Theranostics

P Kumar, D Zelena, A Gautam - Theranostic Applications of …, 2024 - Springer
Neurological disorders encompass multifaceted and heterogeneous ailments that influence
the whole body though the central and peripheral nervous systems. These conditions give …