Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …

A spinal cord injury interrupts the communication between the brain and the region of the
spinal cord that produces walking, leading to paralysis 1, 2. Here, we restored this …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

Cerebral strokes can disrupt descending commands from motor cortical areas to the spinal
cord, which can result in permanent motor deficits of the arm and hand. However, below the …

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

Here, we introduce the Tabulae Paralytica—a compilation of four atlases of spinal cord
injury (SCI) comprising a single-nucleus transcriptome atlas of half a million cells, a …

A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

A spinal cord injury interrupts pathways from the brain and brainstem that project to the
lumbar spinal cord, leading to paralysis. Here we show that spatiotemporal epidural …

Optoelectronic neural interfaces can leverage the photovoltaic effect to convert light into
electrical current, inducing charge redistribution and enabling nerve stimulation. This …