Deep learning in ophthalmology: the technical and clinical considerations

DSW Ting, L Peng, AV Varadarajan, PA Keane… - Progress in retinal and …, 2019‏ - Elsevier
The advent of computer graphic processing units, improvement in mathematical models and
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …

[HTML][HTML] Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

H Gylling, J Plat, S Turley, HN Ginsberg, L Ellegård… - Atherosclerosis, 2014‏ - Elsevier
Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning

R Poplin, AV Varadarajan, K Blumer, Y Liu… - Nature biomedical …, 2018‏ - nature.com
Traditionally, medical discoveries are made by observing associations, making hypotheses
from them and then designing and running experiments to test the hypotheses. However …

Retinal vessel calibers in predicting long-term cardiovascular outcomes: the atherosclerosis risk in communities study

SB Seidelmann, B Claggett, PE Bravo, A Gupta… - Circulation, 2016‏ - ahajournals.org
Background: Narrower retinal arterioles and wider retinal venules have been associated
with negative cardiovascular outcomes. We investigated whether retinal vessel calibers are …

Physical activity as a determinant of successful aging over ten years

B Gopinath, A Kifley, VM Flood, P Mitchell - Scientific reports, 2018‏ - nature.com
We aimed to examine the temporal association between physical activity and successful
aging. The analyses involved 1,584 adults aged 49+ years living west of Sydney (Australia) …

Retinal and choroidal vascular changes in coronary heart disease: an optical coherence tomography angiography study

J Wang, J Jiang, Y Zhang, YW Qian… - Biomedical optics …, 2019‏ - opg.optica.org
To reveal the association between retinal microvasculature changes and coronary heart
disease (CHD), we assessed the full retinal thicknesses of eight areas, the vessel density of …

Retinal vascular caliber: systemic, environmental, and genetic associations

C Sun, JJ Wang, DA Mackey, TY Wong - Survey of ophthalmology, 2009‏ - Elsevier
Quantitative studies of retinal vascular caliber using new computer-assisted retinal imaging
systems have allowed physicians and researchers to understand the influence of systemic …

Prediction of incident stroke events based on retinal vessel caliber: a systematic review and individual-participant meta-analysis

K McGeechan, G Liew, P Macaskill… - American journal of …, 2009‏ - academic.oup.com
The caliber of the retinal vessels has been shown to be associated with stroke events.
However, the consistency and magnitude of association, and the changes in predicted risk …

Meta-analysis: retinal vessel caliber and risk for coronary heart disease

K McGeechan, G Liew, P Macaskill, L Irwig… - Annals of internal …, 2009‏ - acpjournals.org
Background: Retinal vessel caliber may be a novel marker of coronary heart disease (CHD)
risk. However, the sex-specific effect, magnitude of association, and effect independent of …

Retinal vessel diameter and cardiovascular mortality: pooled data analysis from two older populations

JJ Wang, G Liew, R Klein, E Rochtchina… - European heart …, 2007‏ - academic.oup.com
Aims The retinal microvasculature may reflect pre-clinical changes in the cerebral and
coronary microcirculations. We assessed whether smaller retinal arterioles and larger …