From obesity to hippocampal neurodegeneration: pathogenesis and non-pharmacological interventions

TH Lee, S Yau - International journal of molecular sciences, 2020 - mdpi.com
High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Physical exercise consequences on memory in obesity: A systematic review

RAL De Sousa, LG Santos, PM Lopes… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with changes in memory. Thus, the aim of this systematic review was
to investigate the physical exercise consequences on memory in obesity. A search was …

High-intensity interval training-induced hippocampal molecular changes associated with improvement in anxiety-like behavior but not cognitive function in rats with …

A Orumiyehei, K Khoramipour, MH Rezaei… - Brain Sciences, 2022 - mdpi.com
(1) Background: Exercise exerts many neuroprotective effects in diabetes-induced brain
disorders. In this study, we investigated the effect of high-intensity interval training (HIIT) on …

Swimming suppresses cognitive decline of HFD-induced obese mice through reversing hippocampal inflammation, insulin resistance, and BDNF level

H Zhang, JL Liang, QY Wu, JX Li, Y Liu, LW Wu… - Nutrients, 2022 - mdpi.com
Obesity is an important public health problem nowadays. Long-term obesity can trigger a
series of chronic diseases and impair the learning and memory function of the brain. Current …

Aerobic exercise training improves memory function through modulation of brain-derived neurotrophic factor and synaptic proteins in the hippocampus and prefrontal …

I Sadri, SD Nikookheslat, P Karimi, M Khani… - Journal of Diabetes & …, 2024 - Springer
Abstract Aims/Introduction Defective insulin signaling in the brain may disrupt hippocampal
neuroplasticity resulting in learning and memory impairments. Thus, this study investigated …

Moderate-intensity aerobic exercise enhanced dopamine signaling in diet-induced obese female mice without preventing body weight gain

HA Emmons, SC Fordahl - Neuroscience, 2024 - Elsevier
Obesity continues to rise in prevalence and financial burden despite strong evidence linking
it to an increased risk of develo** several chronic diseases. Dopamine response and …

Long-term consequences of COVID-19 on mental health and the impact of a physically active lifestyle: a narrative review

L Roever, BRR Cavalcante… - Annals of General …, 2023 - Springer
Abstract Background Coronavirus-19 disease (COVID-19) is caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Respiratory viruses damage not only the …

Neuroplasticity to autophagy cross-talk in a therapeutic effect of physical exercises and irisin in ADHD

A Abdulghani, M Poghosyan, A Mehren… - Frontiers in molecular …, 2023 - frontiersin.org
Adaptive neuroplasticity is a pivotal mechanism for healthy brain development and
maintenance, as well as its restoration in disease-and age-associated decline. Management …

The role of IGF-1 in exercise to improve obesity-related cognitive dysfunction

Y He, Q Wang, H Wu, Y Dong, Z Peng, X Guo… - Frontiers in …, 2023 - frontiersin.org
Obesity is an important factor that threatens human health. The occurrence of many chronic
diseases is related to obesity, and cognitive function decline often occurs with the onset of …

Protective effects of niacin following high fat rich diet: an in-vivo and in-silico study

N Samad, N Manzoor, A Batool, A Noor, S Khaliq… - Scientific Reports, 2023 - nature.com
Niacin had long been understood as an antioxidant. There were reports that high fat diet
(HFD) may cause psychological and physical impairments. The present study was aimed to …