Current advances in digital cognitive assessment for preclinical Alzheimer's disease

F Öhman, J Hassenstab, D Berron… - Alzheimer's & …, 2021 - Wiley Online Library
There is a pressing need to capture and track subtle cognitive change at the preclinical
stage of Alzheimer's disease (AD) rapidly, cost‐effectively, and with high sensitivity …

Spatial navigation deficits—overlooked cognitive marker for preclinical Alzheimer disease?

G Coughlan, J Laczó, J Hort, AM Minihane… - Nature Reviews …, 2018 - nature.com
Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify
preclinical individuals and target potentially disease-modifying therapies towards them …

Entropy of city street networks linked to future spatial navigation ability

A Coutrot, E Manley, S Goodroe, C Gahnstrom… - Nature, 2022 - nature.com
The cultural and geographical properties of the environment have been shown to deeply
influence cognition and mental health,,,,–. Living near green spaces has been found to be …

Explaining world‐wide variation in navigation ability from millions of people: citizen science project sea hero quest

HJ Spiers, A Coutrot… - Topics in cognitive …, 2023 - Wiley Online Library
Navigation ability varies widely across humans. Prior studies have reported that being
younger and a male has an advantage for navigation ability. However, these studies have …

Global determinants of navigation ability

A Coutrot, R Silva, E Manley, W De Cothi, S Sami… - Current Biology, 2018 - cell.com
Human spatial ability is modulated by a number of factors, including age [1–3] and gender
[4, 5]. Although a few studies showed that culture influences cognitive strategies [6–13], the …

Toward personalized cognitive diagnostics of at-genetic-risk Alzheimer's disease

G Coughlan, A Coutrot, M Khondoker… - Proceedings of the …, 2019 - pnas.org
Spatial navigation is emerging as a critical factor in identifying preclinical Alzheimer's
disease (AD). However, the impact of interindividual navigation ability and demographic risk …

[HTML][HTML] Moving experimental psychology online: How to obtain high quality data when we can't see our participants

JM Rodd - Journal of Memory and Language, 2024 - Elsevier
The past 10 years have seen rapid growth of online (web-based) data collection across the
behavioural sciences. Despite the many important contributions of such studies, some …

Vector-based pedestrian navigation in cities

C Bongiorno, Y Zhou, M Kryven, D Theurel… - Nature computational …, 2021 - nature.com
How do pedestrians choose their paths within city street networks? Researchers have tried
to shed light on this matter through strictly controlled experiments, but an ultimate answer …

Predicting real world spatial disorientation in Alzheimer's disease patients using virtual reality navigation tests

V Puthusseryppady, S Morrissey, H Spiers, M Patel… - Scientific Reports, 2022 - nature.com
Spatial navigation impairments in Alzheimer's disease (AD) have been suggested to
underlie patients experiencing spatial disorientation. Though many studies have highlighted …

Wayfinding across ocean and tundra: what traditional cultures teach us about navigation

P Fernandez-Velasco, HJ Spiers - Trends in Cognitive Sciences, 2024 - cell.com
Research on human navigation by psychologists and neuroscientists has come mainly from
a limited range of environments and participants inhabiting western countries. By contrast …