Hepatocyte regeneration in acute fulminant and nonfulminant hepatitis: a study of proliferating cell nuclear antigen expression

HK Wolf, GK Michalopoulos - Hepatology, 1992 - journals.lww.com
It has been suggested that in fulminant hepatitis it is the lack of hepatocyte regeneration that
in the presence of an ongoing loss of hepatocytes leads to hepatic failure and ultimately …

Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury

A Okajima, K Miyazawa… - European journal of …, 1990 - Wiley Online Library
Overlap** cDNA clones for rat hepatocyte growth factor (rHGF) were isolated by cross‐
hybridization with the cloned cDNA for human hepatocyte growth factor (hHGF) and the …

Identification of a liver growth factor as an albumin-bilirubin complex

JJ Diaz-Gil, JG Gavilanes, G Sanchez… - Biochemical …, 1987 - portlandpress.com
We have reported the purification and characterization of a protein that behaves as a liver
growth factor, showing activity either in vivo or in vitro [Díaz-Gil et al.(1986) Biochem. J. 235 …

[PDF][PDF] Identification of biliprotein as a liver growth factor

JJ Díaz‐Gil, G Sánchez, C Trilla, P Escartín - Hepatology, 1988 - Wiley Online Library
We determined the concentration of biliprotein in plasma of rats at different times after partial
hepatectomy. From the same plasma samples, we purified a liver growth factor previously …

Antioxidant activity of liver growth factor, a bilirubin covalently bound to albumin

L Condezo-Hoyos, F Abderrahim, MV Conde… - Free Radical Biology …, 2009 - Elsevier
We previously reported that treatment of spontaneously hypertensive rats (SHR) with liver
growth factor (LGF), an albumin–bilirubin complex with a covalent bond, reduces blood …

Plasma hepatocyte growth factor and biliprotein levels and outcome in fulminant hepatic failure

RD Hughes, L Zhang, H Tsubouchi, Y Daikuhara… - Journal of …, 1994 - Elsevier
Plasma levels of growth factors may be important in determining the extent of liver
regeneration in patients with fulminant hepatic failure and in this study human hepatocyte …

Human hepatocyte growth factor in blood of patients with fulminant hepatic failure: I. Clinical aspects

H Tsubouchi, S Hirono, E Gohda, H Nakayama… - Digestive diseases and …, 1991 - Springer
The levels of human hepatocyte growth factor (hHGF) in sera obtained from patients with
various liver diseases were determined using adult rat hepatocytes maintained in primary …

Liver growth factor antifibrotic activity in vivo is associated with a decrease in activation of hepatic stellate cells

JJ Díaz-Gil, C García-Monzón, C Rúa… - Histology and …, 2009 - digitum.um.es
The antifibrotic activity of Liver Growth Factor (LGF), a liver mitogen, was previously
demonstrated in several models of rat liver fibrosis and even in extrahepatic sites, such as …

Liver growth factor as a tissue regenerating factor in neurodegenerative diseases

R Gonzalo-Gobernado… - Recent Patents on …, 2014 - benthamdirect.com
Liver growth factor (LGF) is a hepatic mitogen purified by our group in 1986. In the following
years we demonstrated its activity both in “in vivo” and “in vitro” systems, stimulating …

A liver DNA synthesis promoter induced in rat plasma by injection of dimethylnitrosamine (DMNA) or thioacetamide

JJ Diaz-Gil, G Sanchez, L Santamaria, C Trilla… - British journal of …, 1987 - nature.com
The appearance of a liver DNA synthesis promoter (HP) in rat plasma after
dimethylnitrosamine (DMNA) or thioacetamide injection was investigated. After 48 h, DMNA …