Recent advances in the development of liquid crystalline nanoparticles as drug delivery systems

JSL Leu, JJX Teoh, ALQ Ling, J Chong, YS Loo… - Pharmaceutics, 2023 - mdpi.com
Due to their distinctive structural features, lyotropic nonlamellar liquid crystalline
nanoparticles (LCNPs), such as cubosomes and hexosomes, are considered effective drug …

Lyotropic liquid crystalline 2D and 3D mesophases: Advanced materials for multifunctional anticancer nanosystems

H Araújo-Silva, PV Teixeira, AC Gomes, M Lúcio… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cancer remains a leading cause of mortality. Despite significant breakthroughs in
conventional therapies, treatment is still far from ideal due to high toxicity in normal tissues …

Development of N-alkylated benzimidazole based cubosome hydrogel for topical treatment of burns

M Nawaz, S Hayat, U Farooq, MA Iqbal, SH Khalid… - RSC …, 2024 - pubs.rsc.org
The current study focuses on assessing the activity of the N-alkylated benzimidazole based
cubosomal hydrogel (cubogel) for the topical treatment of burn wounds. The study involves …

Clarithromycin-tailored cubosome: A sustained release oral nano platform for evaluating antibacterial, anti-biofilm, anti-inflammatory, anti-liver cancer, biocompatibility …

HD Abdullah, I Kamal, SA Sabry - International Journal of Pharmaceutics, 2024 - Elsevier
The clinical implication of clarithromycin (CLT) is compromised owing to its poor solubility
and, subsequently, bioavailability, unpalatable taste, rapid metabolism, short half-life …

Nuclear Magnetic Resonance Studies of Bicontinuous Liquid Crystalline Phases of Cubic Symmetry: Transport Properties from 2H Nuclear Magnetic Resonance …

O Söderman - Langmuir, 2023 - ACS Publications
The ternary system didodecyltrimethylammonium bromide, 1-decanol, and water forms an
extended reversed continuous phase of cubic symmetry at 25° C. The cubic phase belongs …

Cubosomes as Delivery System to Repositioning Nitrofurantoin in Breast Cancer Management

D Louis, CMZ Rizkalla, A Rashad - Drug Design, Development and …, 2023 - Taylor & Francis
Purpose Nitrofurantoin (NITRO), a long-standing antibiotic to treat urinary tract infections, is
activated by Nitro reductases. This activation mechanism has led to its exploration for …

Formulation and Evaluation of Polymeric Spherical Agglomerates-Based Porous Orodispersible Tablets of Cilnidipine

Y Alhamhoom, SS Prakash, A Kumar, SH Nanjappa… - Pharmaceutics, 2025 - mdpi.com
Background/Objectives: Cilnidipine (CIL) is a calcium channel blocker that exhibits low
bioavailability (~ 13%) due to poor aqueous solubility and extensive pre-systemic gut wall …

Caracterização de cubossomos não-iônicos em presença de proteínas modelo: uma abordagem estrutural e funcional

HS Torres - 2024 - teses.usp.br
Uma área de pesquisa que vem ganhando muita atenção nos últimos anos é a
nanomedicina, com especial atenção para os sistemas com entrega controlada de …

[PDF][PDF] A Contemporary Approach to The Medicate Conveyane Through Orodispersible Tablets

R Prajapati, H Sharma, S Patra, S Makarani… - Int. J. Sci. R …, 2024 - ijsrtjournal.com
The development of dosage forms that are easy to manufacture and administer, as well as
rapid release and increased bioavailability, have led to new drug delivery systems. To …