Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease
EJ Seo, N Fischer, T Efferth - Pharmacological research, 2018 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …
of this disease remains incompletely understood and safe and effective therapies are …
Vitamin D in neurological diseases
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …
a possible risk factor for the development of many neurological diseases. Recent studies are …
Vitamin D in neurological diseases: a rationale for a pathogenic impact
It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …
Vitamin D and Parkinson's disease
A Pignolo, S Mastrilli, C Davì, V Arnao, P Aridon… - Nutrients, 2022 - mdpi.com
Vitamin D is a fat-soluble secosteroid, traditionally considered a key regulator of bone
metabolism, calcium and phosphorous homeostasis. Its action is made possible through the …
metabolism, calcium and phosphorous homeostasis. Its action is made possible through the …
The role of vitamins in neurodegenerative disease: An update
Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
Vitamin D deficiency accelerates ageing and age‐related diseases: a novel hypothesis
MJ Berridge - The Journal of physiology, 2017 - Wiley Online Library
Ageing can occur at different rates, but what controls this variable rate is unknown. Here I
have developed a hypothesis that vitamin D may act to control the rate of ageing. The basis …
have developed a hypothesis that vitamin D may act to control the rate of ageing. The basis …
Vitamin D supplementation worsens Alzheimer's progression: Animal model and human cohort studies
RH Lai, CC Hsu, BH Yu, YR Lo, YY Hsu, MH Chen… - Aging …, 2022 - Wiley Online Library
Vitamin D deficiency has been epidemiologically linked to Alzheimer's disease (AD) and
other dementias, but no interventional studies have proved causality. Our previous work …
other dementias, but no interventional studies have proved causality. Our previous work …
Precision Nutrition for Alzheimer's Prevention in ApoE4 Carriers
The ApoE4 allele is the most well-studied genetic risk factor for Alzheimer's disease, a
condition that is increasing in prevalence and remains without a cure. Precision nutrition …
condition that is increasing in prevalence and remains without a cure. Precision nutrition …
Targeting nuclear receptors in neurodegeneration and neuroinflammation
S Willems, D Zaienne, D Merk - Journal of medicinal chemistry, 2021 - ACS Publications
Nuclear receptors, also known as ligand-activated transcription factors, regulate gene
expression upon ligand signals and present as attractive therapeutic targets especially in …
expression upon ligand signals and present as attractive therapeutic targets especially in …
[HTML][HTML] Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders
Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …